17,261 trials
Colorectal Neoplasms
Primary: Objective Response Rate (ORR) Based on Response Evaluation Criteria in Solid Tumors, Version 1.1 (RECIST 1.1) — 5.0; 5.0 Percentage of Participants
Advanced Renal Cell Carcinoma · Advanced Sarcomatoid Renal Cell Carcinoma · Stage III Renal Cell Cancer AJCC v7
Primary: Observed Response Rate — 0; 11 percentage of patients responding
Hyperparathyroidism · Hypercalcemia · Parathyroid Neoplasm
Primary: Type of Hyperparathyroidism — 90; 276; 19; 61 Participants
Exocrine Pancreatic Insufficiency (EPI) · Cystic Fibrosis (CF)
Primary: Efficacy of MS1819-SD: Coefficient of Fat Absorption (CFA) — 55.6; 86.2 % CFA
Advanced Parkinson's Disease
Primary: Levodopa Cmax Following First Dose on Day 1 — 2857.56; 2173.30 ng/mL
Sickle Cell Disease · Vaso-occlusive Pain Episode
Primary: Total Parenteral Opioid Use in IV Morphine Equivalents — 1.77; 1.95; 2.36 mg/Kg
COVID-19
Primary: Composite of Mortality, Ongoing Need for Hospitalization, or Mechanical Ventilation at Day 15 — 9; 19 Participants — p=0.667
Pyoderma Gangrenosum
Primary: The Proportion of Subjects Achieving 2-point Reduction in the 5-point Investigator Global Assessment (IGA) for the Target Ulcer at Week 12 — 0 Participants — p=1
Coronavirus Disease 2019
Primary: Time to Recovery — 3.4; 3.7; 3.9 Days
Healthy Volunteers
Primary: Virus Infection — 8; 18 Participants
Chemotherapy Induced Anemia
Primary: Maximum Change in Hb Within 16 Weeks From Baseline Without Red Blood Cell (RBC) Transfusion — 2.47 g/dL
Breast Cancer
Primary: Cohort A: Recommended Phase2 Dose (RP2D) — 400 mg
EBV-Related Post-Transplant Lymphoproliferative Disorder · Monomorphic Post-Transplant Lymphoproliferative Disorder · Polymorphic Post-Transplant Lymphoproliferative Disorder
Primary: Percentage of Patients Assigned to Arm Latent Membrane Protein-specific T-cells (LMP-TC) With Successful LMP-specific T Cell Product Match, Were Treated Within Two Weeks…
Non Small Cell Lung Cancer
Primary: Overall Survival — 27.6; 12.7; NA months
Type 1 Diabetes
Primary: Percentage of Time With Sensor Glucose Values Between 70 and 180 Milligrams Per Deciliter (mg/dL) With Continuous Glucose Monitoring (CGM) — 71.57; 65.76; 70.18…