4,901 trials
Cancer
Primary: Response and Progression Will be Evaluated in This Study Using the New International Criteria Proposed by the Response Evaluation Criteria in Solid Tumors (RECIST)…
Erectile Dysfunction
Primary: Maximum Observed Plasma Concentration (Cmax) — 292.60; 121.00 ng/mL
Type 2 Diabetes Mellitus
Primary: Saxagliptin Pharmacokinetic (PK) Parameter Area Under the Plasma Concentration Versus Time Curve From Time 0 Extrapolated to Infinity (AUC[0-inf]) — 49.23; 49.94; 52.50…
Healthy
Primary: Area Under the Curve From Time Zero to Infinite Time [AUC (0 - ∞)] — 2833; 2821 ng*hr/mL
Infections, Bacterial
Primary: Area Under the Curve of Plasma Concentration of Drug From Time 0 (Zero) to t (Last Measurable Concentration) (AUC0-t) — 36431.460; 40426.451 ng per hour per ml…
Cancer
Primary: Mean (SD) Pharmacokinetic (PK) Parameter Area Under Concentration Time Curve From Zero to Infinity (AUC0-oo) — 600; 731; 720 ng*hr/mL
Type 2 Diabetes
Primary: Number of Participants Who Experienced at Least One Adverse Event — 3; 1; 1; 2 participants
Depression - Major Depressive Disorder
Primary: Area Under the Plasma Concentration-time Profile From Time 0 to 48 Hours (AUC48) — 2948; 2966; 2632; 2777 ng*hr/mL
Advanced Solid Tumors
Primary: Excretion Balance of Radio-labeled 14C-eribulin: Total Recovery of Radioactive Dose in Urine and Feces. — 90.4 percent recovery
Insomnia
Primary: Number of Participants Whose Standard Deviation of Lateral Position (SDLP) Following Active Treatment As Compared to Placebo In Relation To The 2.5 cm SDLP Threshold…
Glaucoma, Open-Angle · Ocular Hypertension
Primary: Change From Baseline in Worse Eye Intraocular Pressure (IOP) at Day 14 — 25.98; 26.58; 26.45; 25.93 Millimeters of mercury (mm Hg)
Influenza
Primary: Number of Participants Reporting Adverse Events by System Organ Class After Vaccination With ACAM FLU A, or ACAM FLU A With Adjuvant, or a Placebo Vaccine. — 2; 2; 1; 0…
Overactive Bladder (OAB) With Symptoms of Frequency, Urgency, and Urgency
Primary: Area Under the Curve From Time Zero to Extrapolated Infinite Time [AUC (0 - ∞)] for Fesoterodine Metabolite (5-hydroxymethyltolterodine [5-HMT]) — 30.48; 28.24; 19.64…
Malignant Melanoma
Primary: T 1/2 — 9.94 hr
Healthy
Primary: Area Under the Concentration-Time Curve From Zero Time Until the Last Sampling Time (AUCt) — 126.36; 129.48; 122.33; 119.75 ng*h/mL