65,437 trials
Spinal Ischemia · Stroke · Neuroprotection
Primary: Death or Neurologic Disability, Defined as an National Institutes of Health Stroke Scale (NIHSS)>4 or American Spinal Injury Association (ASIA) Lower Extermity Motor…
Cystic Fibrosis · Liver Fibrosis
Primary: Elastographic Value in kPa Measured by Fibroscan — 4.7 kPa
Osteoarthritis
Primary: Rate of Progression of Joint Space Narrowing — -0.101; -0.125; -0.109 mm/year — p=0.508770
Rheumatoid Arthritis
Primary: Number of Participants With Adverse Events (AEs) and Serious Adverse Events (SAEs) — 17; 9; 6; 2 Participants
Obesity
Primary: Percent Excess Weight Loss (%EWL) at Week 12 — 11.9; 2.7 Percentage of Excess Weight Loss
Smoking Cessation
Primary: 7 Day Point Prevalence Abstinence From All Forms of Tobacco — 2; 2 participants
Psoriasis
Primary: Dose-response Efficacy Profile of AMG 827 Compared With Placebo as Measured by the Percent Improvement From Baseline in Psoriasis Area and Severity Index (PASI) Score at…
Autoimmune Hepatitis
Primary: Biochemical Response to Therapy — 14; 21 Participants
Breast Cancer
Primary: Progression-Free Survival (PFS) — 9.9 months
Influenza Infection
Primary: Seroconversion Rate of Hemagglutination Inhibition (HI) Antibody Titer (Egg-Derived Antigen) — 47.7; 46.0; 31.2; 36.0 percentage of participants
Anesthesia
Primary: Cmax of Oxymetazoline and PBBA — 1.79; 465 ng/mL
Anesthesia
Primary: The Proportion of Subjects Receiving Kovacaine Mist Who do Not Require Rescue Anesthesia During the Operative Dental Procedure — 10; 7; 8 participants
Chronic Renal Failure
Primary: Mean Percent of Successful HD Sessions — 99.9 Percentage of HD Sessions
Schizophrenia Prodrome
Primary: Scale of Prodromal Symptoms Total Score — 37.8; 37.5 units on a scale
Generalized Anxiety Disorder
Primary: Comparisons of End of Study HAM-A Score Means for Sertraline 50 mg vs Placebo, Sertraline 100 mg vs Placebo, and Sertraline 50 mg vs. Sertraline 100 mg — 10.638; 10.008…