N/A N=64 Supporting Refugee and Immigrant Youth's Mental Health
Mental Health
Primary: Strengths and Difficulties Questionnaire — 4.91; 3.49; 2.72; 2.72 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=116 A Study of JNJ-55308942 in the Treatment of Bipolar Depression
Bipolar Disorder
Primary: Change From Baseline in Montgomery-Asberg Depression Rating Scale (MADRS) Total Score up to Week 6 — -16.0; -15.4 Units on a scale — p==0.438
N/A N=130 Telemedicine Optimized Burn Intervention
Burns · Pediatric ALL
Primary: Number of Participants Who Agree to Participate in the Study — 66; 64 participants
Phase 2 N=22 Testing the Addition of a New Anti-Cancer Drug, Niraparib, to the Usual Treatment (Hormone and Radiation Therapy) for Prostate Cancer With a High Chance of Recurring
Prostate Adenocarcinoma · Stage IIC Prostate Cancer AJCC v8 · Stage III Prostate Cancer AJCC v8
Primary: Number of Participants Disease-free Until Completion of Treatment (2 Years From Start of ADT)
Phase 3 N=352 SI-6603 (Condoliase) Study for Lumbar Disc Herniation (Discovery 6603 Study)
Lumbar Disc Herniation
Primary: Change From Baseline to Week 13 in Average Worst Leg Pain Score During the Past 24 Hours Over the Previous 7 Days — -41.7; -34.2 units on a scale — p=0.0263
N/A N=28 Adapting Body Reprogramming for Severe Asthma: a Feasibility Study
Severe Asthma
Primary: Number of Participants Taking Part Who Completed All 4 Weeks of the Course — 13 Participants
N/A N=68 Seroma Formation After Modified Radical Mastectomy With Flap Fixation Technique in Breast Cancer Patients
Breast-cancer
Primary: Seroma Formation — 54.27; 59.56; 102.21; 117.94 ml — p=<0.005
N/A N=89 Comparing Virtual Reality (VR) to Non-VR for Decreasing Preoperative/Procedural Anxiety
Preoperative Anxiety
Primary: Preoperative Anxiety Score in Pediatric Oncology Patients — 31.44; 28.26; 45.38; 32.81 score on a scale
N/A N=6 Evaluation of the Ability of Newly Developed Adhesives to Absorb Moisture
Stoma Ileostomy
Primary: Resistance (Moisture in the Adhesive) — 0; 0 Number of false positive leaks
Phase 4 N=101 A Study to Evaluate the Safety and Efficacy of Nivolumab With Ipilimumab in Participants With Untreated Advanced Kidney Cancer Conducted in India
Kidney Neoplasms
Primary: Total Number of Participants Experiencing High Grade Immune-Mediated Adverse Events (IMAE) — 2; 1; 2; 1 Participants
N/A N=248 Real-time Effort Driven VENTilator Management
Ventilation Therapy; Complications · Diaphragm Disease · Pediatric Respiratory Diseases
Primary: Median Duration of Weaning — 0.09; 1.04; 2.03; 2.10 days — p=.045
Phase 2 N=121 Lerapolturev in Recurrent Malignant Glioma
Malignant Glioma
Primary: Number of Participants With Objective Radiographic Response — 5; 2 Participants
N/A N=780 Effect of Expanding (Gloving) Barrier Precautions for Reducing Clostridium Difficile Acquisition (and Infection) in VA
Clostridium Difficile
Primary: C. Difficile Acquisition Rates — 13.2; 10.4 C. diff acquisition per patient days — p=0.611
Phase 3 N=129 Adjunctive GNX Treatment Compared With Placebo in Children and Adults With TSC-related Epilepsy
Tuberous Sclerosis Complex
Primary: Percent Change From Baseline in 28-day Seizure Frequency for Primary Seizure Type During Double Blind Period — -7.50; 13.57 Percent change — p=0.0904
Phase 4 N=300 Clinical Study of Lipoic Acid on Ischemic Heart Failure
Ischemic Heart Failure
Primary: Number of Participants That Had First Occurrence of the Composite Endpoint — 32; 40 Participants