6,678 trials
Fabry Disease
Primary: Percent Change From Baseline in Interventricular Septum and Left Ventricular Posterior Wall Thickness at Week 156 — -3.31; -6.34 percent change
Rheumatoid Arthritis
Primary: Percentage of CD27+ Switched Memory B Cells at Week 12 — 13.2; 13.8 Percentage of B Cells — p=0.3
Open-Angle Glaucoma · Ocular Hypertension
Primary: Mean Nocturnal IOP at Week 4 — 24.2; 23.6; 18.6; 18.9 mmHg
Alcohol Dependence · Major Depression · Social Anxiety Disorder
Primary: Percent Days Drinking — 34.9; 31.9 percentage of days drinking — p=0.64
Blood Loss · Tranexamic Acid · Cardiac Surgery
Primary: Postoperative Blood Loss — 290; 300; 290 ml
Impaired Glucose Tolerance (IGT)
Primary: Assessment of Diabetic Status in the Treatment Period (Type 2 Diabetes Mellitus, Normoglycemia, or Impaired Glucose Tolerance (IGT) — 25; 106; 66 participants
Schizophrenia · Psychotic Disorders
Primary: Positive Syndrome Scale (PANSS) Total Score — -1.05; -1.30 units on a scale
Multiple Sclerosis
Primary: Peak Activity Index — 0.6; 0.3 change in strides per minute — p=0.586
Rotavirus Disease
Primary: Percentage of Participants Achieving Seroresponse for Diphtheria Toxin, Tetanus Toxin, Pertussis Filamentous Hemagglutinin (FHA), and Poliovirus Type 1, 2, and 3 — 100…
Dupuytren's Contracture
Primary: Number Patients Obtaining Clinical Improvement (>50% Reduction in Contracture) — 5; 1 participants
Episodic Migraine
Primary: Change in Headache Intensity — -47.6; -20.7 percent change
Common Cold
Primary: Total Symptom Score (TSS) Over Days 2 to 4 (TSS2-4) — 6.390; 5.777 units on a scale — p=0.0895
Metabolic Syndrome
Primary: CT Angiography Plaque — 0.17; -1.53 percent change of low attenuation plaque
Weight Maintenance · Overweight · Obese
Primary: Mean Change in Body Weight From Baseline to End of 24 Weeks — 1.62; -0.62 kg
Brain Neoplasms, Malignant, Primary
Primary: Cmax — 11.108; 10.575 mcg/mL — p=<0.05