Phase 4 N=24 Effect of Deep BLock on Intraoperative Surgical Conditions
Prostate Hypertrophy · Renal Disease
Primary: Surgical Rating Scale — 4; 4.7 units on a scale (1-5) — p=<0.001
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=366 Randomized Trial of Vitamin B12 in Pregnant Indian Women
Pregnancy
Primary: Changes in Maternal Serum B12 Concentration From 1st to 3rd Trimester — 3.0; -37.6 pmol/L
N/A N=86 Clinical Effects and Safety of 3% Diquafosol After Cataract Surgery
Dry Eye Syndromes
Primary: an Ocular Surface Disease Index (OSDI) Questionnaire That is Related to Dry Eye Severity. — 21.09; 23.00; 31.28; 20.31 scores on a scale — p=0.221
Phase 4 N=17 Study of Brain Response to Emotional Pictures Using a Magnetic Resonance Imaging (fMRI) While on Escitalopram
Major Depression
Primary: 17-item Hamilton Depression Rating Scale (HAM-D) — 18; 19; 6; 6 units on a scale
Phase 2 N=158 Efficacy and Safety Study of iSONEP With & Without Lucentis/Avastin/Eylea to Treat Wet AMD
Exudative Age-related Macular Degeneration
Primary: Mean Change in Best Corrected Visual Acuity (BCVA) by Early Treatment Diabetic Retinopathy Study (ETDRS) — -3.17; 4.22; 3.63; 4.34 letters
N/A N=1,292 Study for Validation of Standardized Questionnaires on Depression and Investigation of the Frequency of Depression in Rheumatoid Arthritis (RA) Participants
Rheumatoid Arthritis
Primary: PHQ-9 Score at Baseline: VADERA I — 5.2 scores on a scale — p=<0.001
N/A N=600 Prospective Observational Study of Clostridium Difficile Infection in Asian Pacific Countries
Clostridium Difficile Infection
Primary: Patient Demographics — 54; 46; 63; 29 participants
N/A N=160 Reduced Exposure Study in Smokers Using the Tobacco Heating System 2.2 (THS 2.2) for 5 Days in a Confinement Setting
Smoking
Primary: Concentration of Monohydroxybutenyl Mercapturic Acid (MHBMA) — 106.25; 460.15; 91.73 pg/mg creat — p=<0.001
Phase 3 N=20 Phase 3 Study to Evaluate the Acid-Inhibitory Effect of Multiple Oral Doses of Vonoprazan (TAK-438)
Healthy Volunteers
Primary: Intragastric pH Time Course Over 24 Hours — 10.63; 10.63; 8.90; 8.90 percentage of time
Phase 3 N=328 A Study to Assess the Efficacy and Tolerability of Diclofenac Potassium Soft Gelatin Capsules Compared With Ibuprofen Tablets in Patients With Moderate to Severe Postoperative Dental Pain
Post Operative Dental Pain
Primary: Change From Baseline in Visual Analog Scale of Pain Intensity (VASPI) at 60 Minutes Post Dose — 47.3; 44.1 units on a scale — p=0.211
Phase 2 N=80 MK2206 and Erlotinib Hydrochloride in Treating Patients With Advanced Non-Small Cell Lung Cancer Who Have Progressed After Previous Response to Erlotinib Hydrochloride Therapy
Adenosquamous Lung Carcinoma · Bronchioloalveolar Carcinoma · Large Cell Lung Carcinoma
Primary: Disease-control Rate — 40; 43 percentage of subjects
Phase 4 N=46 FMRI Study of Brain Response Before and After Lithium Treatment in People With Bipolar Disorder
Bipolar Disorder
Primary: 17-item Hamilton Depression Rating Scale (HDRS) — 20; 6; 6; 2 units on a scale
N/A N=78 Effect of Nitrous Oxide in Treating Neuropathic Pain: A Study in Chronic Low Back Pain Patients
Low Back Pain · Radiating Pain
Primary: Change in VAS Pain Score From Baseline to 3 Month Follow-up — -1.6; -1.2 units on a scale — p=0.84
Phase 2 N=142 Pharmacodynamic Effects of Lixisenatide Compared to Liraglutide in Patients With Type 2 Diabetes Not Adequately Controlled With Insulin Glargine With or Without Metformin
Type 2 Diabetes Mellitus
Primary: Change From Baseline to Day 56 in Plasma Glucose Corrected Area Under The Plasma Concentration-Time Curve (AUC) From Time 0.5 Hours to 4.5 Hours — -13.33; -7.32; -8.72…
Phase 3 N=232 A Non-Comparative Study to Assess the Safety of MabThera (Rituximab) in Patients With Rheumatoid Arthritis.
Rheumatoid Arthritis
Primary: Number of Participants With Any Adverse Event, Any Serious Adverse Event, and Death — 189; 12; 0 participants