Phase 4 N=60 One Hour Preoperative Gatifloxacin
Ophthalmic Surgery
Primary: Number of Participant With Positive Culture — 17 participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=11 Pharmacokinetics, Safety, and Tolerability of Subcutaneous GAMUNEX-C in Pediatric Subjects With Primary Immunodeficiency
Primary Immunodeficiency
Primary: Steady-state Area Under the Curve (AUC) for Serum Total Immunoglobulin (IgG) — 216873.7; 230830.0 h*mg/dL
Phase 4 N=70 The Efficacy of Solifenacin With or Without Tamsulosin in Adult Women With Overactive Bladder (OAB)
Overactive Bladder
Primary: Change in Mean Number of Micturition Episodes Per 24 Hours — -1.9; -2.2 episodes
Phase 4 N=130 Effect of Probiotics on Gut-Liver Axis of Alcoholic Liver Disease
Alcoholic Liver Disease
Primary: Liver Enzymes(ALT) — 66; 48 IU/L
Phase 4 N=63 Open-label, Test-retest Study Assessing Reproducibility of Quantitative Measurements of Myocardial Uptake of AdreView.
Heart Failure (HF) · Ventricular Dysfunction, Left
Primary: To Assess Test-retest Reproducibility of Iobenguane I 123 Injection Myocardial Uptake in Heart Failure (HF) Participants on Planar Imaging at 3 Hours 50 Minutes…
Phase 4 N=334 Effects of the Combination of Bosentan and Sildenafil Versus Sildenafil Monotherapy on Pulmonary Arterial Hypertension (PAH)
Pulmonary Arterial Hypertension
Primary: Time to First Confirmed Morbidity/Mortality Event up to the End of Study — 96.1; 90.6; 90.5; 83.0 percentage of participants-Kaplan Meier — p=0.2508
Phase 4 N=116 Preventing Propofol Injection Pain: Prospective Randomized Trial Comparing Propofol Versus Fospropofol
Complication of Injection · Pain
Primary: Compare Incidence and Intensity of Pain on Injection That is Caused by Propofol (Lipid Emulsion) Versus the Test Drug Fospropofol.
Phase 4 N=28 Functional Magnetic Resonance Imaging (fMRI) Study of Nasal Strips in Nasal Congestion
Nasal Congestion
Primary: Anatomical Measures : Cross Sectional Area — 133.22; 116.88; 156.48; 176.12 mm^2 — p=<0.0001
Phase 4 N=46 Milnacipran for Chronic Pain in Knee Osteoarthritis
Knee Osteoarthritis · Degenerative Joint Disease · Chronic Pain
Primary: McGill Pain Questionnaire - Short Form — 10.5; 15.7; 6.0; 12.3 units on a pain scale
Phase 4 N=82 Study of Oasis Ultra in Diabetic Foot Ulcers
Diabetic Foot Ulcer
Primary: Percentage of Wounds Closed — 54; 32 percentage of wounds closed
Phase 4 N=300 Post-operative Dental Pain Study Comparing Analgesic Efficacy
Post-surgical Dental Pain
Primary: Sum of Pain Relief and Pain Intensity Differences From 0 to 6 Hours (SPRID 6 Hours) — 10.60; 5.87; 3.35 Units on a scale — p=0.0004
Phase 4 N=11 Study of Sirolimus Versus Mycophenolate Liver Transplant Recipients With Recurrent Hepatitis C Virus (HCV)
Hepatitis C
Primary: Delta Hepatitis C Viral Load — 15 percent change
Phase 4 N=60 Spinal Anaesthesia With Levobupivacaine 0.5% and Ropivacaine 0.75% for Lower Limb Orthopaedic Surgery
Lower Limb Surgery
Primary: Duration of Analgesia — 309.83; 249.50 minutes
Phase 4 N=10 Cystagon to Treat Infantile Neuronal Ceroid Lipofuscinosis
Infantile Neronal Ceroid Lipofuscinosis
Primary: Change in Cellular Granular Osmiophilic Deposits (GRODs) in Electron Micrographs of Peripheral White Blood Cells. — -0.3317 Average number of GRODs
Phase 4 N=68 A Study of Glucocorticoid Use to Evaluate Systematic Methylprednisolone Reduction in Patients With Rheumatoid Arthritis on Background RoActemra/Actemra (Tocilizumab) (ACT-ALONE)
Rheumatoid Arthritis
Primary: Median GC Dose Taken During the Noninterventional Phase — 6; 6; 4; 0 mg