Phase 2 N=56 Medication Development in Alcoholism: Investigating Glucocorticoid Antagonists
Alcoholism
Primary: Craving to Drink — 36.5; 42.9 units on a scale — p=.003
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=57 Rhodiola Rosea Therapy of Major Depressive Disorder
Depression
Primary: Depressive Symptoms as Measured by the Hamilton Depression Rating Scale (17-items) at Week 8 and Week 12. — 8; 8.3; 8.9; 7.9 units on a scale
Phase 2 N=84 Dl-3-n-butylphthalide and Cerebrolysin Treatment in Acute Ischemic Stroke
Acute Cerebral Stroke Within 12 Hours for the First Time
Primary: National Institutes of Health Stroke Scale Score — 8.78; 7.80; 8.85; 5.48 units on a scale
N/A N=16 Dynamic Magnetic Resonance Imaging (MRI) for Lung Tumor Motion and Lung Function (GCC 0943)
Lung Cancer
Primary: Number of Participants Whose Tumor Position is Visible Within ~2mm Using Cine-MRI Scans and External Sensors — 7 participants
Phase 1 N=31 Panitumumab in Children With Solid Tumors
Solid Tumors
Primary: Number of Participants With Dose-limiting Toxicities (DLTs) — 1; 0; 0; 1 participants
Phase 3 N=465 Efficacy and Safety of Ozenoxacin 1% Cream Versus Placebo in the Treatment of Patients With Impetigo
Impetigo
Primary: Clinical Success — 34.8; 19.2; 37.7 percentage of participants — p=0.003
N/A N=240 Cholesterol Medication Packaging Study
Hypercholesterolemia
Primary: Cholesterol Medication Adherence — .99; .94 adherence proportion — p=0.300
Phase 2 N=26 Paclitaxel, Ifosfamide, and Carboplatin Followed By Autologous Stem Cell Transplant in Treating Patients With Germ Cell Tumors That Did Not Respond to Cisplatin
Brain and Central Nervous System Tumors · Extragonadal Germ Cell Tumor · Ovarian Cancer
Primary: Response — 12; 6; 5 participants
N/A N=57 Efficacy of Leg Casts With Heel Off-loaded in Children
Orthopedic Disorders
Primary: Pain Score on the "Numeric Rating Scale" or "Visual Rating Scale" or "Face, Legs Activity Cry Consolability" According to Age Group — 4.4; 3.9 units on a scale
Phase 3 N=120 MIRACLE Study: A Study of Once-Monthly Intravenous Mircera in Hemodialysis Participants With Chronic Renal Anemia
Anemia
Primary: Percentage of Participants Who Maintained Average Hb Within Plus/Minus (±) 1 g/dL of Reference Hb or Within Target Range During the Efficacy Evaluation Period (EEP)…
Phase 3 N=201 Long-term Extension Trial of Asenapine in Subjects With Schizophrenia (Study P06125)
Schizophrenia
Primary: Percentage of Participants in Categories of Change in Weight From Study P06124 Baseline to Final Assessment — 12.9; 26.8; 64.5; 61.6 percentage of participants in category
Phase 4 N=80 Analgesia After Total Shoulder Arthroplasty
Total Shoulder Arthroplasty
Primary: Numeric Rating Scale (NRS) Pain Score With Movement — 4.5; 3.4; 4.2; 4.9 units on a scale
N/A N=934 Surgical Resection With or Without Axillary Lymph Node Dissection in Treating Women With Node-Negative Breast Cancer and Sentinel Lymph Node Micrometastases
Breast Cancer
Primary: 5-year Disease-Free Survival — 84.4; 87.8 percentage of participants — p=0.004
Phase 4 N=10 A Study Of Pregabalin (Lyrica) Drug Levels In Urine, Plasma And Breast Milk Of Healthy Lactating Women
Healthy Lactating Women
Primary: Area Under the Curve From Time Zero to End of Dosing Interval (AUCtau) — 32.50 microgram*hour/milliliter (mcg*hr/mL)
Phase 2 N=38 Omega-3 Fatty Acids For Treatment Of Young Children With Autism (OMG)
Autism Spectrum Disorder
Primary: Change From Baseline in the Pervasive Developmental Disorder-Behavioral Inventory (PDDBI) - Autism Composite Score — -4.5; -6.4 units on a scale — p=0.5