Phase 4 N=104 Treatment of Binge Eating in Obese Patients in Primary Care
Obesity · Binge Eating
Primary: Binge Eating (Remission) — 10; 8; 6; 6 participants — p=0.60
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=139 Use of Electrical Impedence to Measure Lean Body Weight as a Determinant of the Dose of Contrast Media for Abdominal CT
IV Contrast Dosing
Primary: Difference in Enhancement of the Liver and Blood Vessels Over Time, Measured in Hounsfield Units (HU) — 116; 124; 121; 120 Hounsfield units (HU)
Phase 4 N=226 Evaluation of Intravenous Cardene(Nicardipine)and Labetalol Use in the Emergency Department
Hypertensive Urgency
Primary: Percentage of Subjects Achieving a Pre-defined Target Systolic Blood Pressure (BP) Within 30 Minutes. — 91.7; 82.5 percentage of participants — p=0.04
Phase 4 N=459 Effectiveness of Vyvanse Compared to Concerta in Adolescents With Attention-deficit/Hyperactivity Disorder
Attention-deficit/Hyperactivity Disorder
Primary: Change From Baseline in Attention-Deficit/Hyperactivity Disorder Rating Scale, Fourth Edition (ADHD-RS-IV) Total Score at Week 8 — -13.4; -25.6; -23.5 units on a scale…
Phase 4 N=24 An Investigator Initiated, Within-Subject, Proof of Concept Study to Assess the Efficacy and Safety of Voltaren Gel in Subjects With DOMS
Pain · Delayed Onset Muscle Soreness
Primary: Mean Reduction in SPID Scores of DOMS on Walking Over 24 Hours — 34.87; 23.62 units on a scale — p=0.0324
Phase 4 N=20 Efficacy Study of Montelukast in Atopic Dermatitis Induced by Food Allergens
Atopic Dermatitis
Primary: Change in Percentage of Body Involvement — -2.0; 0.15 Change of percentage in body involvement
Phase 4 N=39 Mechanisms of Sleep Latency and Health: The Effect of a Melatonin Receptor Agonist in Inflammation and Insulin Resistance
Insomnia
Primary: Sleep Onset Latency (SOL) as Measured by Self Report (Sleep Diary) — 29.7; 24.8 minutes
Phase 4 N=40 Randomized Controlled Trial on the Treatment Effects of Melatonin and Light Therapy on Delayed Sleep Phase Syndrome
Delayed Sleep Phase Syndrome
Primary: To Investigate the Efficacy on Rise Time of Bright Light Therapy and Melatonin Treatment Using a 4 Armed Placebo Controlled Design. Main Outcome Measures: Sleep Log…
Phase 4 N=41 Human Immunodeficiency Virus (HIV), Arterial Dysfunction, Lipids, Lovaza (HALO) Trial
Cardiovascular Disease · HIV Infection
Primary: Change in Baseline Mean Serum Triglyceride Level at Study End — -103.0; -23.4 mg/dl
Phase 4 N=450 15 Month Study for Adults Who Have Been Diagnosed With Schizophrenia and Incarcerated
Schizophrenia
Primary: Time to First Treatment Failure — 416; 226 Days
Phase 4 N=2,776 Study of Tomography of Nephrolithiasis Evaluation
Urolithiasis
Primary: High Risk Diagnosis With Complication — 6; 3; 2 participants
Phase 4 N=89 Multicenter, Randomized, Open-label Study to Assess Whether Treatment With Mycophenolate Sodium (MPS) Allows Higher Dose Optimization Versus Mycophenolate Mofetil (MMF) Leading to a Dose Reduction of Tacrolimus. Maximiza Study.
Prophilaxis of Acute Rejection in Patients Receiving a Renal Allograft
Primary: Number of Participants Achieving at Least Two Mycophenolic Acid (MPA) Dose Steps Higher and Reducing Tacrolimus Dose at the End of the Study — 0; 0; 43; 38 number of…
Phase 4 N=16 Exploratory Muscle Biopsy Assessment Study in Patients With Late-Onset Pompe Disease Treated With Alglucosidase Alfa
Pompe Disease (Late-Onset) · Glycogen Storage Disease Type II (GSD II) · Glycogenesis 2 Acid Maltase Deficiency
Primary: Change From Baseline in Tissue Glycogen Content in Quadriceps Muscle Biopsy Samples at Week 26 — 5.3; -1.6 percent area occupied by glycogen — p=0.1860
Phase 4 N=68 Study to Evaluate the Efficacy of Rotigotine on Parkinson's Disease-Associated Pain
Advanced Idiopathic Parkinson's Disease
Primary: Change From Baseline to the End of the Maintenance Period in Pain Severity Assessed Using an 11-point Likert Pain Scale — -2.2; -2.8 scores on a scale — p=0.172
Phase 4 N=99 Rehabilitation of the Stroke Hand at Home
Stroke
Primary: Action Research Arm Test (ARAT) — 39.47; 39.89 units on a scale