Phase 3 N=2,414 MK-0524B Lipid Study (MK-0524B-063)
Primary Hypercholesterolemia · Mixed Dyslipidemia
Primary: Percentage Change From Baseline in Low-density Lipoprotein Cholesterol (LDL-C) — -44.6; -46.9; -48.9; -50.4 Percentage Change
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=70 Evaluation of Dual Channel vs. Single Channel FES for Dropfoot
Dropfoot
Primary: Ankle Movement as Good as or Better With the Segmented Electrode as With the QFE — 3.63 units on a scale
N/A N=311 Safe Play Areas for Ross County Kids Project
Other Specified Personal Exposures and History Presenting Hazards to Health · Knowledge, Attitudes, Practice · Fall Involving Playground Equipment, Occurrence on Farm
Primary: Change in Playground Hazards — 50; 0; 0; 0 % increase playgrounds w/surfacing
N/A N=1,858 Changes in Physical Functioning in Patients With COPD During Therapy With a Combination Inhalation Therapy
Pulmonary Disease, Chronic Obstructive
Primary: Percentage of Participants With "Therapeutic Success" — 48.90; 51.10 Percentage of participants
Phase 3 N=418 Evaluate the Maintenance of Efficacy of SPD489 in Adults Aged 18-55 Years With Moderate to Severe Binge Eating Disorder
Binge Eating Disorder
Primary: Time to Relapse From Date of Randomization to Endpoint of The Randomized-withdrawal Period — NA; NA days — p=<0.001
Phase 2 N=85 Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis With(J-M-Pa-Z) (NC-001)
Pulmonary Tuberculosis
Primary: Early Bactericidal Activity (EBA) Measured as the Mean Rate of Change of log10 Colony Forming Units (CFU) of M. Tuberculosis Per ml Sputum on Solid Medium Over Time…
Phase 2 N=16 An Implantable Microneuromodulator for the Treatment of Chronic Shoulder Pain in Chronic Post-Stroke Subjects
Shoulder Pain Chronic
Primary: Relief of Chronic Shoulder Pain — 0; 0 participants
Phase 4 N=40 Harmonic ACE®+7 Shears in Laparoscopic Colectomy
Benign or Malignant Disease Indicated for Colectomy
Primary: Percentage of Participants With Hemostasis at the IMA — 100.0 percentage of subjects
Phase 4 N=31 ACE Inhibitors to Decrease Lymphoid Fibrosis in Antiretroviral-Treated, HIV-infected Patients: A Pilot Study
HIV
Primary: Change in HIV RNA (Copies/Million Rectal Cells) — 1.1; -0.2 copies/million rectal cells — p=0.63
Phase 4 N=18 Bisphosphonate Therapy for Osteogenesis Imperfecta
Osteogenesis Imperfecta · Osteoporosis · Paget Disease of Bone
Primary: Bone Mineral Density — -1.3; -1.1 z-score
Phase 2 N=60 Neoadjuvant Chemotherapy With Methotrexate, Vinblastine, Adriamycin and Cisplatin (M-VAC) Plus Avastin in Patients With Urothelial Cancer
Bladder Cancer
Primary: Percentage of Participants With Response Defined as the Absence of Residual Muscle Invasive Cancer in Resected Specimen — 38; 53 Percentage of Participants
N/A N=191 Handling Comparison Between Two Contact Lens Types
Presbyopia
Primary: Overall Lens Handling Using the Contact Lens User Experience(CLUE) TM Questionnaire. — 53.44; 55.81; 61.70; 60.23 units on a scale
Phase 4 N=80 Study Using Pregnenolone to Treat Bipolar Depression
Bipolar Disorder · Major Depressive Disorder
Primary: The 17-item Hamilton Rating Scale for Depression (HRSD17) — 9.18; 9.41 units on a scale — p=0.9084
N/A N=10 Interscalene Dynamometer Pilot Study
Total Shoulder Arthroplasty
Primary: Anterior Deltoid Strength — 77 percent
Phase 3 N=14 A Study of Tocilizumab in Patients With Rheumatoid Arthritis Who Have an Inadequate Response to Current Non-Biologic DMARDs
Rheumatoid Arthritis
Primary: Percentage of Participants With Adverse Events (AEs) or Serious Adverse Events (SAEs) — 92.9; 7.1 percentage of participants