Phase 1 N=24 Drug - Drug Interaction Study of Quinine Sulfate and Ciprofloxacin
Healthy
Primary: Maximum Plasma Concentration(Cmax) — 4,240.65; 4,521.20 ng/mL
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 1 N=26 A Study to Compare the Bioavailability of Two Tramadol Hydrochloride Tablet Products (50 mg and 200 mg, Respectively) at Steady-state Under Fasting Conditions
Healthy Subjects · Pharmacokinetics · Bioavailability
Primary: Area Under the Plasma Concentration Versus Time Data Pairs at Steady State (AUCss) — 5991; 6399 ng*h/mL
Phase 1 N=36 Study of Two Tramadol Contramid® OAD 300 mg Controlled-Release Tablets From Two Different Manufacturing Sites Following a 300 mg Dose in Healthy Subjects Under Fasting and Fed Conditions
Healthy
Primary: AUC(0-t) — 9708; 9696; 9431 ng.h/mL
Phase 1 N=54 Fed Bioequivalence Study of Fenofibric Acid Versus TriCor® (Fenofibrate)
Healthy
Primary: Maximum Plasma Concentration (Cmax) — 8,545.50; 9,456.66 ng/mL
Phase 1 N=37 Four Arm Food Effect Study of Fenofibric Acid Tablets
Healthy
Primary: Maximum Plasma Concentration (Cmax) — 9,806.74; 9,854.39; 7,950.75; 12,061.67 ng/mL
Phase 1 N=30 Drug-Drug Interaction Study Between Fenofibric Acid and Efavirenz
Healthy
Primary: Maximum Plasma Concentration (Cmax) of Efavirenz — 2,461.58; 2,384.79 ng/mL
Phase 1 N=12 Effect of Calcium Glycerophosphate (CaGP) - Fluoride Dentifrice on Dental Biofilm pH
Dental Caries
Primary: Minimum pH — 5.40; 5.48; 5.25; 5.70 pH — p=0.001
Phase 1 N=548 Clinical Equivalence of Two Butenafine Hydrochloride 1% Creams in Patients With Interdigital Tinea Pedis
Tinea Pedis
Primary: Therapeutic Cure - Superiority Analysis — 76; 108; 24 Participants — p=0.0127
Phase 1 N=54 Bioequivalence Study of Fenofibric Acid Versus Tricor® (Fenofibrate)
Healthy
Primary: Maximum Plasma Concentration (Cmax) — 12,344.00; 10,940.05 ng/mL
Phase 1 N=22 A Drug-Food Interaction Study Between Colchicine and Grapefruit Juice
Pharmacokinetics
Primary: Maximum Plasma Concentration (Cmax) — 2,172.96; 1,971.10 pg/mL
Phase 1 N=24 Drug-Drug Interaction Study Between Colchicine and Diltiazem ER
Healthy; Adult; Volunteer; Colchicine; Pharmacokinetics; Diltiazem; Cytochrome p450 3A4; P-glycoprotein
Primary: Maximum Plasma Concentration (Cmax) — 2,172.32; 2,802.90 pg/mL
Phase 1 N=24 Drug-Drug Interaction Study of Colchicine and Clarithromycin
Pharmacokinetics
Primary: Maximum Plasma Concentration (Cmax) — 2.84; 8.44 ng/mL
Phase 1 N=24 Drug-Drug Interaction Between Colchicine and Verapamil ER
Pharmacokinetics
Primary: Maximum Plasma Concentration (Cmax) — 2,968.42; 3,850.63 pg/mL
Phase 1 N=24 Drug-Drug Interaction Between Colchicine and Ritonavir
Pharmacokinetics
Primary: Maximum Plasma Concentration (Cmax) — 1,869.50; 4,993.06 pg/mL
Phase 1 N=24 Drug-Drug Interaction Study Between Colchicine and Ketoconazole
Pharmacokinetics
Primary: Maximum Plasma Concentration (Cmax) — 2,779.08; 5,266.92 pg/mL