Phase 4 N=44 Long Term Antihypertensive Exposure and Adverse Metabolic Effects: PEAR Follow-Up Study
Drug Induced Hyperglycemia · Secondary Hyperlipidemia
Primary: Fasting Glucose (mg/dL) — 94 mg/dL
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=109 Atazanavir/Ritonavir, Once Daily + Raltegravir, Twice Daily, Switch Study in HIV-1-Infected Patients
HIV, Combination Therapy
Primary: Percentage of Participants With HIV-1 RNA Level <40 c/mL at Week 24 — 80.6; 94.6 Percentage of participants
Phase 4 N=249 Catheter Evaluation for Endocardial Ablation in Patients With Ventricular Tachycardia
Ventricular Tachycardia
Primary: The Percentage of Subjects That Expire From All-cause Mortality Within 12-months Post Ablation. — 13.3 percentage of mortality
Phase 4 N=328 Rasagiline as Add on to Dopamine Agonists in the Treatment of Parkinson's Disease
Parkinson's Disease
Primary: Change From Baseline to Week 18 in the Unified Parkinson's Disease Rating Scale (UPDRS) Total Score for Parts I, II and III — -3.6; -1.2 units on a scale — p=0.012
Phase 4 N=176 A Study Evaluating the Persistency of Response With or Without Xolair (Omalizumab) After Long-term Therapy
Allergic Asthma
Primary: Percentage of Participants Not Experiencing a Protocol-defined Severe Exacerbation During the Study — 67.0; 47.7 Percentage of participants
Phase 4 N=135 Efficacy & Safety of KAPVAY™ Extended-Release in Children & Adolescents With Attention Deficit Hyperactivity Disorder
Attention Deficit Hyperactivity Disorder
Primary: Long-term Maintenance of Efficacy of KAPVAY in Children and Adolescents With Attention Deficit Hyperactivity Disorder (ADHD) as Measured by the Percentage of Treatment…
Phase 4 N=20 A Study to Evaluate the Tolerability of Botox and Topiramate or Botox and Placebo and Effect on Cognitive Efficiency
Chronic Migraine
Primary: Subject Attrition Post Randomization — 1; 2; 1; 1 participants
Phase 4 N=23 A Pharmacokinetic Study of CellCept (Mycophenolate Mofetil) Versus Mycophenolate Sodium in Kidney Transplant Patients
Kidney Transplantation
Primary: Pre-dose Trough Concentration (C0) — 2.387; 2.944 mg/L — p=0.8055
Phase 4 N=127 Treatment of Myofascial Pain Syndrome With Lidocaine Injection and Physical Therapy.
Myofascial Pain Syndrome · Pain · Myofascial Trigger Point Pain
Primary: Visual Analogue Scale — 40.8; 44.2; 37.8 units on a scale
Phase 4 N=35 Vitamin D Plus Fluticasone Propionate
Seasonal Allergic Rhinitis
Primary: Change From Baseline in Total Nasal Symptom Score (TNSS) Over 2 Week Randomized Treatment Period — -11.3; -7.6 units on a scale — p=0.09
Phase 4 N=640 A Study to Assess Efficacy and Safety With Solifenacin Succinate to Improve Urinary Continence After Robotic Assisted Radical Prostatectomy
Urinary Incontinence
Primary: Time From First Dose to Urinary Continence — NA; NA days — p=0.1745
Phase 4 N=99 A Pilot Study to Evaluate the Efficacy of Montelukast in the Treatment of Acute Otitis Media (AOM) in Children
Acute Otitis Media · Otitis Media · Ear Infection
Primary: Incidence of Acute Otitis Media — 30; 27 participants with AOM
Phase 4 N=31 Randomized Trial to Evaluate Suppressive Effect of High-Dose Acyclovir Versus Once-Daily Valacyclovir on Persons With HSV-2
Genital Herpes
Primary: Frequency of HSV-2 Total Shedding From the Genital Tract as Measured by PCR, Calculated Using a Per-day Shedding Rate in Participants Treated With High-dose Acyclovir as…
Phase 4 N=63 12-Week Study of Pristiq (Desvenlafaxine) Social Anxiety Disorder
Social Anxiety Disorder
Primary: Change in the Liebowitz Social Anxiety Scale (LSAS) Total Score — 93.4; 92.1; 55.0; 63.4 Scores on a scale
Phase 4 N=26 Effects of Escitalopram on Autonomic Reactivity in Post Traumatic Stress Disorder
PTSD
Primary: High Frequency Heart Rate Variability — 6.31; 5.48 ln(msec)