Phase 4 N=10 Dose-Response of Salmeterol in Children
Asthma
Primary: Total Airway Resistance Increase — 47; 22.9 ln(mg/mL)
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=141 Counseling for Primary Care Office-based Buprenorphine
Opiate Dependence
Primary: Illicit Opioid Abstinence — 10.29; 10.12 Weeks of Abstinence — p=.91
Phase 4 N=84,496 Study Evaluating the Effiacy of a 13-Valent Pneumococcal Conjugate Vaccine (13vPnC) in Adults
Pneumonia, Pneumococcal · Pneumococcal Infections · 13-valent Pneumococcal Vaccine
Primary: Number of Participants With First Episode of Confirmed Vaccine-type Community-acquired Pneumonia (VT-CAP) — 49; 90 participants — p=0.0006
Phase 4 N=19 A Study of Memantine Hydrochloride (Namenda®) for Cognitive and Behavioral Impairment in Adults With Autism Spectrum Disorders
Autism Spectrum Disorders
Primary: Number of Participants With Reduction in ASD Symptom Severity as Defined by the Social Responsiveness Scale (SRS) — 6 participants
Phase 4 N=2,902 Immunogenicity, Safety and Tolerability of a Trivalent Subunit Inactivated Vaccine in Healthy Subjects 50 Years and Above
Influenza
Primary: Hemagglutination Inhibition (HI) Geometric Mean Titers (GMTs) of TIV Group and TIVf Group for All Three Strains, in Healthy Adults Aged ≥50 Years — 315; 581; 697; 1048…
Phase 4 N=60 Study to Evaluate the Effects Icodextrin Versus Dianeal on Insulin Resistance in Nondiabetic Automated Peritoneal Dialysis Patients
Disorders Associated With Peritoneal Dialysis
Primary: Adjusted HOMA Index Score at 3 Months Using Baseline Values as a Covariate and Groups as the Fixed Factor — 1.49; 1.89 IR score
Phase 4 N=60 Post Market Clinical Follow-up Study
Hip or Knee Surgery
Primary: Minimize the Risk of the Development of Blistering. — 60 participants
Phase 4 N=87 A Study of CellCept (Mycophenolate Mofetil) Combined With Calcineurin Inhibitors in Liver Transplant Patients.
Liver Transplantation
Primary: Percentage of Participants With Decrease in Glomerular Filtration Rate (GFR) of Greater Than 20% — 5.4; 0.0 percentage of participants — p=0.494
Phase 4 N=25 Randomized, Double Blind, 2 Way Crossover Study of CSII With, Versus Without, Pretreatment With Human Hyaluronidase
Type 1 Diabetes Mellitus
Primary: Early Insulin Exposure (%AUC[0-60]) — 33.53; 17.85; 39.45; 33.52 percentage of AUC(0-60) — p=<0.0001
Phase 4 N=479 Efficacy of Everolimus-Eluting Versus Zotarolimus-Eluting Sten for Coronary Lesions in Acute Myocardial Infarction
Myocardial Infarction
Primary: Device-oriented Composite Outcome — 12; 13 participants
Phase 4 N=81 Effect of Lactobacillus Plantarum 299v on Symptoms of Irritable Bowel Syndrome
Irritable Bowel Syndrome
Primary: A Change in Abdominal Pain Severity — 259.66; 256.04; 199.13; 201.98 units on a scale — p=<0.05
Phase 4 N=34 A Pharmacodynamic Study With Ticagrelor in African American Patients
Stable Coronary Artery Disease
Primary: Inhibition of the P2Y12 Receptor as Measured by Platelet Reaction Unit (PRU) From VerifyNow™ (a Platelet Function Test Developed by Accumetrics) at 2 Hours After Loading…
Phase 4 N=64 Effect of Molsidomine on the Endothelial (Internal Layer of Blood Vessels) Dysfunction in Patients With Angina Pectoris
Stable Angina Pectoris · Atherosclerosis
Primary: Change Versus Baseline in the Score of the EndoPAT in the Two Groups After One Year of Treatment (Month 12). — 330.60; 164.08 Relative change versus baseline (%)
Phase 4 N=60 Safety and Immunogenicity Among Healthy Children Receiving Fluzone® Quadrivalent Influenza Virus Vaccine
Influenza
Primary: Number of Participants Reporting Solicited Injection-Site or Systemic Reactions Following Vaccination With the 2013-2014 Formulation of Fluzone® Quadrivalent, Influenza…
Phase 4 N=72 Alternate Dosing Schedules Study for HPV Vaccine
Cervical Cancer · Genital Warts
Primary: Pain Following HPV Vaccine — 17; 32 participants