12,372 trials
Glabellar Lines
Primary: The Percentage of Responders at Day 29 Cycle 1 as Measured by Investigator's Live Assessment (ILA) of Glabellar Lines at Maximum Frown: DB Period — 81.6; 0.8 Adjusted…
Chemotherapeutic Agent Toxicity · Colorectal Cancer · Neuropathy
Primary: Sensory Area Under the Curve(AUC) Score. Oxaliplatin-induced Sensory Neuropathy as Repeatedly Measured by the EORTC QLQ-CIPN20 Sensory Subscale During Chemotherapy…
Pantothenate Kinase-Associated Neurodegeneration
Primary: Change in Score on Barry-Albright Dystonia Scale — 2.48; 3.99 score on a scale — p=0.0761
Acute Coronary Syndrome
Primary: 7-Day Point Prevalence Smoking Abstinence — 70; 49 Participants
Asthma
Primary: Change From Baseline in Morning (AM) Post-Dose % Predicted Forced Expiratory Volume in One Second (FEV1) in the Area Under the Curve (AUC)0-60 — 79.21; 78.48; 8.99; 3.96…
Chronic Obstructive Pulmonary Disease COPD
Primary: Mean Change From Baseline in Morning Pre-dose Trough Forced Expiratory Volume in 1 Second (FEV1) Over 24 Weeks — 82.4; 169.6 milliliter (mL) — p=0.9974
Drug Addiction
Primary: Sleep Efficiency as Assessed by Percentage of Time Asleep While in Bed — 78; 74 percentage of time asleep while in bed
Acquired Thrombotic Thrombocytopenic Purpura
Primary: Time to Platelet Count Response — 2.69; 2.88 days — p== 0.0099
Depressive Disorder, Treatment-Resistant
Primary: Time to Relapse in Participants With Stable Remission (Maintenance Phase) — NA; 273.0 Days — p== 0.003
Pulmonary Arterial Hypertension
Primary: Number of Participants With at Least One Adverse Event (AE) — 15 Participants
Colorectal Cancer
Primary: Overall Survival — 7.1; 5.3 months — p=<0.0001
Hepatitis C Virus
Primary: Percentage of Participants With Extended Rapid Virologic Response (eRVR) - Part A — 51.9 Percentage of participants
Overactive Bladder
Primary: Change in the Mean Daily Number of Urination Episodes at Week 12 — 12.5; 11.9; 9.0; 8.6 urination episodes per day — p==0.5595
Hyperkalemia
Primary: Exponential Rate of Change in Serum Potassium (S-K) Values During the Initial 48 Hours of Study Drug Treatment — -0.00273; -0.00508; -0.00012 log (mmol/L) / hour…
Caries
Primary: Percentage Surface Microhardness Recovery (%SMH) — 13.96; 30.59; 40.74; 48.28 Percent Surface Microhardness Recovery