65,437 trials
Sedation to be Moderate for a Diagnostic Gastrointestinal Endoscopy and Gastrointestinal Endoscopic Polypectomy
Primary: Achivement of Target Sedation — 21.6; 88.1; 94.5 % of patients — p=<0.001
Pancreatic Exocrine Insufficiency Due to Cystic Fibrosis
Primary: Coefficient of Fat Absorption (CFA) — 88.1; 89.5 percentage of fat intake
Thyroid Cancer
Primary: Overall Response Rate (ORR) for Vandetanib 150 and 300mg With Responses Determined by the Investigator — 0.20; 0.29 Proportion of participants
Body Weight · Contraceptive Usage
Primary: LNG Steady State at Baseline and Then Post-randomization — 3.82; 3.13; 3.01; 3.58 ng/mL
Chronic Kidney Disease · Cardiovascular Disease · Death
Primary: Recurrent or de Novo Arteriosclerotic Cardiovascular Disease (CVD) Defined as the Occurrence of Non-fatal or Fatal Arteriosclerotic Outcomes Including Coronary Heart…
Major Depressive Disorder
Primary: Number of Participants With Adverse Events (AEs) or Serious AEs (SAEs) — 2; 1; 0; 75 participants
Depressive Disorder · Depression · Depressive Disorder, Major
Primary: Change From Baseline (End of Phase A [Week 8]) to Week 14 in Montgomery-Asberg Depression Rating Scale (MADRS) Total Score for the Efficacy Sample. — -8.27; -5.15 Units…
Premenopausal Breast Cancer
Primary: Percentage of Participants With Suppressive Effect of Serum Estradiol (E2) to Menopausal Level (=<30 pg/mL) From Week 4 Through Week 48 — 97.6; 96.4 percentage of…
Rheumatoid Arthritis
Primary: Adjusted Geometric Mean of Maximum Observed Serum Concentration (Cmax) of a Single Dose of Subcutaneous (SC) Abatacept - PK-Evaluable Analysis Population — 11.5; 12.6…
Benign Prostatic Hyperplasia
Primary: Responder Analysis: A Subject is a Responder at the 12 Month Follow-up Time Point if All 6 Thresholds of the BPH-6 Endpoint Are Met — 52; 20 % Responders of Participants
Diabetes · Diabetes Mellitus, Type 2
Primary: Change From Baseline in HbA1c (%) (Glycosylated Haemoglobin) — 0.10; -0.74; -0.39 percentage of glycosylated haemoglobin
Depressive Symptoms · Diabetes Mellitus
Primary: Depressive Symptoms (CES-D Score) — -7.4; -2.7 Scores on a scale
Kidney Cancer
Primary: Overall Objective Response Rate as Measured by RECIST — 1; 16; 6 participants
Carcinoma · Renal Cell · Non Clear Cell Renal Carcinoma
Primary: To Evaluate Efficacy of RAD001 as Monotherapy for the Treatment of Papillary Renal Cancer. Efficacy is Defined as the Percentage of Patients Progression-free at 6…
Chronic Hepatitis C Infection
Primary: Percentage of Participants With Sustained Virologic Response 24 Weeks After Treatment (SVR24) — 100; 88.9; 100; 100 percentage of participants