Phase 2 N=23 Using Telemedicine to Improve Veteran Sleep Apnea Care
Sleep Apnea Syndromes
Primary: Treatment Adherence — 3.4; 3.6 hours/night
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=29 Pharmacogenetics of Ace Inhibitor-Associated Angioedema
Hypertension · Diabetes Type 2
Primary: The Effect of Enalaprilat (ACE Inhibition), Sitagliptin (DPP4 Inhibition), or the Combination on the Vasodilator Response (Forearm Blood Flow) to Substance P (SP) and…
Phase 2 N=16 Inhaled NO as an Anti-inflammatory and Anti-reperfusion Agent in Infants and Children Undergoing Cardiopulmonary Bypass
Congenital Heart Disease
Primary: Serum Inflammatory Mediators Post CPB — 3.8; 3.4; 90.9; 78.3 ng/mL — p=>0.05
Phase 3 N=555 Ph3 Safety/Efficacy Study of Rolapitant for the Prevention of CINV in Subjects Receiving Highly Emetogenic Chemotherapy
Chemotherapy-induced Nausea and Vomiting
Primary: No Emetic Episodes and No Rescue Medication — 70.1; 61.9 percentage of participants — p=0.043
N/A N=32 Risk Factors for Implant Bone Loss in Patients With Diabetes Mellitus
Diabetes
Primary: Radiographic Bone Level — 2.69; 2.54 mm
Phase 2 N=202 Safety and Immunogenicity of One Dose of Novartis' Meningococcal ACWY-CRM Vaccine and GlaxoSmithKline Biologicals' Meningococcal ACWY-TT Vaccine in Healthy Toddlers
Meningococcal Disease
Primary: Number of Subjects With at Least One Severe Solicited Adverse Event (AE) After Receiving One Dose of Either MenACWY-CRM Vaccine or MenACWY-TT. — 4; 2 Number of Subjects
N/A N=290 An Observational Study of Methoxy Polyethylene Glycol-epoetin Beta in Participants With a Kidney Transplant
Anemia, Kidney Transplantation
Primary: Percentage of Participants With a Hemoglobin Value of 11-12 Grams Per Deciliter (g/dL) From Visit 7 (Month 7) to Visit 9 (Month 9) — 20.7 percentage of participants
Phase 2 N=405 Development of Rational Ways of Medical and Non-medical Treatment Methods for Metabolic Syndrome
Metabolic Syndrome
Primary: Blood Glucose Level — 6.05; 6.43; 4.58; 14.5 mmole/L
Phase 2 N=58 The Effect of NK1R Antagonism on Alcohol Craving and PTSD Symptoms in Alcohol Dependent Patients With PTSD
Alcoholism · Alcohol Dependence · Posttraumatic Stress Disorder
Primary: Alcohol Craving in Response to the Stress Script — 11.9; 12.9 units on a scale
Phase 4 N=50 Anti-Vascular Endothelial Growth Factor (Anti-VEGF) Alone Versus Ozurdex Given Every 3 Months for Treatment of Persistent Diabetic Macular Edema
Diabetic Macular Edema
Primary: Mean Visual Acuity Change — 5.6; 5.8 ETDRS letters
Phase 4 N=65 Duloxetine for Chronic Depression: a Double-blind Study
Dysthymic Disorder · Depressive Disorder NOS
Primary: Hamilton Depression Rating Scale (HDRS) - 24 Total Score — 5; 10 Scores on a scale — p=.003
Phase 1 N=22 Pharmacokinetic-pharmacodynamic Interaction Between Three Different Single Doses of BIA 9-1067 and a Single-dose of Controlled-release 100/25 mg Levodopa/Benserazide
Parkinson's Disease (PD)
Primary: Cmax - Maximum Observed Plasma Concentration of Levodopa — 314; 266; 263; 260 ng/mL
Phase 2 N=25 Human Fetal Liver Cell Transplantation in Chronic Liver Failure
Liver Cirrhosis
Primary: Patient Survival — 5; 6; 4; 10 participants — p=0.4340
N/A N=46 Effect of Healing Time on New Bone Formation Following Tooth Extraction and Ridge Preservation With Demineralized Freeze-Dried Bone Allograft
Bone Augmentation
Primary: Percent New Vital Bone Formation — 32.63; 47.41 percentage of vital bone
Phase 2 N=26 Ixabepilone in Treating Patients With Recurrent or Persistent Leiomyosarcoma of the Uterus Previously Treated With Chemotherapy
Recurrent Uterine Corpus Sarcoma · Uterine Corpus Leiomyosarcoma
Primary: Tumor Response — 0 percentage of participants