17,261 trials
Triple Negative Breast Cancer · Endometrial Cancer · Hormone Receptor Positive, HER2 Negative Breast Cancer
Primary: Cohort 1 - Progression-free Survival (PFS) — 1.9 Months
Adenocarcinoma Gastric Stage IV With Metastases · Adenocarcinoma - GEJ
Primary: Percentage of Participants With Objective Response Rate (ORR) Based on Independent Central Review Following Treatment With DS8201a in Participants With HER2-Positive…
Lung Cancer
Primary: 8-Week Disease Control Rate (DCR) — 0; 0; 3; 3 Participants
Postsurgical Pain
Primary: Pain Intensity Scores — 367.41; 415.27; 373.92; 447.05 scores on a scale*hours — p=0.0004
Waldenstrom's Macroglobulinemia
Primary: Major Response Rate — 26 Participants
Multiple Myeloma
Primary: D-VMP, D-Rd, and D-Kd Cohorts: Overall Response Rate (ORR) — 88.1; 90.8; 84.8 percentage of participants
Covid19
Primary: Number of Serious Adverse Events — 4; 6 Adverse Events
Irritable Bowel Syndrome
Primary: Percentage of Participants With Overall Response — 25.0; 17.1; 23.4; 17.8 Percentage of Participants — p=0.152
Metastatic Medulloblastoma · High Risk Supratentorial PNET · Metastatic PNET
Primary: Event-free Survival — 7 Participants
Metastatic Pancreatic Cancer
Primary: Phase 1b: Number of Participants With Dose Limiting Toxicities (DLTs) — 0; 0; 0 Participants
Neovascular Age-Related Macular Degeneration
Primary: Time to First Rescue Treatment — 5; 4; NA months
End Stage Renal Disease · Anemia
Primary: Number of Participants With Week 7 Hb ≥ Baseline Hb - 0.5 g/dL, Among Normoresponder Participants Treated for 6 Weeks Only — 4; 8; 7; 4 Participants — p=1.0000
Non Small Cell Lung Cancer Metastatic
Primary: Objective Response Rate (ORR) — 32.5 percentage of participants
Biliary Tract Cancer · Cholangiocarcinoma · Gallbladder Cancer
Primary: Percentage of Participants With Confirmed Objective Response According to Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST v1.1) as Assessed by…
COVID-19 Pneumonia
Primary: Time to Recovery, Defined as the Time to a Clinical Status Score of 1 or 2 on the 7-Category Ordinal Scale (Whichever Occurs First) by Day 28 — 10.0; 11.0; 10.0 Days…