N/A N=1,206 Epidemiology of Depression, Anxiety, and Cognitive Impairment
Depression · Anxiety · Cognitive Impairment
Primary: Participants With Depression by Patient Health Questionnaire - 9 — 177 participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=506 Phase 3 Study of Deoxycholic Acid Injection (ATX-101) Versus Placebo for the Reduction of Localized Subcutaneous Fat in the Submental Area
Moderate or Severe Submental Fullness
Primary: Percentage of Participants Who Achieved a Composite 1-grade Response — 70.0; 18.6 percentage of participants — p=<0.001
Phase 2 N=129 Deoxycholic Acid Injection Submental Fat (SMF) Magnetic Resonance Imaging (MRI) and Subject-reported Outcome Measures Study
Moderate or Severe Submental Fullness
Primary: Change From Baseline in Clinician-Reported Submental Fat Rating Scale Scores — -0.7; -0.8; -0.4 units on a scale — p=0.052
Phase 3 N=516 Phase 3 Study of Deoxycholic Acid Injection (ATX-101) Versus Placebo for the Reduction of Localized Subcutaneous Fat in the Submental Area
Moderate or Severe Submental Fullness
Primary: Percentage of Participants Who Achieved a Composite 1-grade Response — 66.5; 22.2 percentage of participants — p=<0.001
N/A N=767 Project Quit: Positive vs. Negative Offers of an Online Stop Smoking Program
Smoking Cessation
Primary: Acceptance of Offer to Join Stop Smoking Program — 288 participants
Phase 2 N=85 Phase 1-2 Study of Deoxycholic Acid Injection (ATX-101) for the Reduction of Submental Fat
Moderate or Severe Submental Fullness
Primary: Number of Participants With Adverse Events — 20; 19; 22; 21 participants
N/A N=146 Antibiotic Prophylaxis in Orthopaedic Traumatology
Fractures, Closed · Wounds and Injuries
Primary: Number of Participants With Total Wound Infections — 4; 9 participants — p==0.12
N/A N=34 Ankle Robotics Training After Stroke
Seated Treadmill Training · Treadmill Locomotor-based Training · Treadmill Only
Primary: Self-selected Floor Walking Velocity Change From Baseline to Post-training and Retention — 56.0; 55.5; 50.9; 56.1 cm/sec — p=< 0.01
Phase 4 N=50 Cognitive Enhancement in Bipolar Disorder
Bipolar Disorder
Primary: Change From Baseline to Week 8 in Weschler Adult Intelligence Scale-Third Edition (WAIS-III) Digit Span Subtest (Digits Forward) — 8.43; 8.54; 8.48; 8.13 number of…
N/A N=50 Enabling Advance Directive Completion
Advance Directives
Primary: Number of Participants Who Completed an Advance Directive — 30; 5 participants
Phase 2 N=207 A Phase 2, Double-Blind, Multiple-Dose Escalation Study to Evaluate NKTR-118 (Oral PEG-Naloxol) in Patients With Opioid-Induced Constipation (OIC)
Opioid Induced Constipation (OIC)
Primary: Change From Baseline in Spontaneous Bowel Movements (SBMs) Per Week During Week 1 — 1.8; 2.6; 1.9; 3.6 Number of SBMs/week — p=0.7781
Phase 2 N=47 Subcutaneous CINRYZE With Recombinant Human Hyaluronidase for Prevention of Angioedema Attacks
Hereditary Angioedema (HAE)
Primary: Normalized Number of Angioedema Attacks During the Treatment Period — 1.58; 0.97 angioedema attacks — p=0.0523
Phase 1 N=33 Pharmacokinetic Interaction Between HGP0904, HGP0608 and HGP1405
Hypertension(HTN)
Primary: AUClast — 1.0360; 1.1606; 1.0266; 1.0902 Ratio(Comb/Alone)
Phase 4 N=52 Switch From Tenofovir to Raltegravir for Low Bone Mineral Density
HIV · Osteopenia · Osteoporosis
Primary: Percent Change in Bone Mineral Density (BMD) of Lumbar Spine and Hips — 2.7; 3.0; 2.3; 1.9 percent change — p=<0.0001
N/A N=36 Influence of Antiretroviral Regimen on Immune Reconstitution in the Female Genital Tract
Women's Health · HIV Infection · Genital Diseases, Female
Primary: CD4+ to CD8+ T Cell Ratio in Cervical Biopsies — 0.46; 0.52 Cervical CD4+:CD8+ T cell ratio — p=0.6