Phase 2 N=42 Raloxifene for Women With Alzheimer's Disease
Alzheimer Disease
Primary: Alzheimer's Disease Assessment Scale, Cognitive Subscale (ADAS-cog) — -3.2; -3.5 units on a scale — p=>0.1
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=30 Clinical Study on Silk Sericin Wound Dressing for Split-thickness Skin Graft Donor Sites Treatment
Late Complication From Skin Graft · Infection of Skin Donor Site · Impaired Wound Healing
Primary: Clinical Efficacy of Wound Dressing Containing Silk Sericin for Split-thickness Skin Graft Donor Site Treatment — 12 Days
Phase 2 N=20 The Study Will Evaluate the Efficacy of AZD5423 in Patients With Mild Asthma Challenged With an Inhaled Allergen
Asthma
Primary: Late Allergic Response (LAR) by Assessment of Minimum Percentage of FEV1 3-7 Hours Post Allergen Challenge Compared to Pre Allergen Challenge FEV1 — 90.97; 91.32; 87.28…
N/A N=193 A Mixed Methods Approach to the Development and Testing of the Measure of Drug Self-Management (MeDS)
Diabetes · Hypertension
Primary: Measure of Medication Self-Management (MeDS) — 10.9; 2.5 units on a scale — p=<.001
Phase 4 N=452 Prevention of Recurrence in Depression With Drugs and CT
Depression
Primary: Number of Participants in Remission According to the Longitudinal Interval Follow-up Evaluation (LIFE) and the Hamilton Rating Scale for Depression (HRSD) — 187; 170…
Phase 3 N=80 Efficacy and Mechanisms of Pharmacologic Treatment of Fecal Incontinence
Fecal Incontinence
Primary: 7-day Bowel Diary, Number of Fecal Incontinence Episodes — 7.3; 7.9; 4.8; 4.1 Fecal incontinence episodes
N/A N=56 22G FNA Needle vs. 22G ProCore Needle
Pancreatic Neoplasm
Primary: Compare the Median Number of Passes Required to Establish a Diagnosis — 1; 1 No. of passes for diagnosis
N/A N=45 Efficacy of Oral Versus Intravenous Acetaminophen for Primary Pediatric Cleft Palate Repair
Cleft Palate
Primary: Opioid (Fentanyl and Morphine) Consumption
Phase 3 N=608 Comparison of Two Medications Aimed at Slowing Aortic Root Enlargement in Individuals With Marfan Syndrome
Marfan Syndrome
Primary: Annual Rate of Change in Aortic Root (Sinuses of Valsalva) Body-surface-area-adjusted Z-score — -0.139; -0.107 z-score/year — p=0.08
Phase 4 N=20 Endocrine Dysfunction and Growth Hormone Deficiency in Children With Optic Nerve Hypoplasia
Growth Hormone Deficiency · Septo-Optic Dysplasia · Hypopituitarism
Primary: Change in Anthropometric Measures Over Time — 1.97; -0.61; 1.39; 1.22 Z-score
Phase 1 N=328 Vitamin D for Chemoprevention
Gastrointestinal Cancers · Prostate Cancer · Hypertension
Primary: Levels of Plasma 25(OH)D at Baseline, 3 Months and 6 Months. — 15.1; 16.2; 13.9; 15.7 ng/mL
Phase 2 N=83 Topical Perillyl Alcohol in Treating Patients With Sun Damaged Skin and Actinic Keratoses
Precancerous Condition
Primary: Change in Histopathology Score of Sun Damaged Skin by Treatment Group — 0.4; -0.1; 0.1 units on a scale — p=0.10
Phase 3 N=641 Oral Treatment for Orthopaedic Post-operative Pain With Dexketoprofen Trometamol and Tramadol Hydrochloride
Acute Pain
Primary: SPID8 (Sum of Pain Intensity Differences Over 8 Hours) — 246.9; 208.8; 204.6; 151.1 units on a scale
Phase 3 N=606 Oral Treatment for Gynaecological Post-operative Pain With Dexketoprofen Trometamol and Tramadol Hydrochloride
Acute Pain
Primary: SPID8 (Sum of Pain Intensity Differences Over 8 Hours) — 241.8; 184.5; 157.3; 117.0 units on a scale
Phase 2 N=180 A Definitive Estrogen Patch Study (ADEPT)
Schizophrenia · Schizoaffective Disorder · Schizophreniform Disorder(Not in Manic Phase)
Primary: Positive and Negative Syndrome Scale (PANSS) — 18.24; 19.18; 18.18; 14.11 units on a scale