12,372 trials
Proliferative Vitreoretinopathy
Primary: Recurrent Retinal Detachment Compared to Historical Rates — 18.8; 20.6 percentage of subjects
Castration-Resistant Prostate Carcinoma · Metastatic Prostate Carcinoma · Stage IVB Prostate Cancer AJCC v8
Primary: Patients Reporting Adverse Reactions — 0 Participants
Diabetes Mellitus, Type 2 · Peripheral Arterial Disease
Primary: Change in Maximum Walking Distance on a Constant Load Treadmill Test — 1.21; 1.08 Ratio of maximum walking distance — p=0.0004
Liposarcoma, Dedifferentiated
Primary: Progression-free Survival (PFS) — 8.18; 8.38; 7.16 Months — p=0.0956
Lennox Gastaut Syndrome
Primary: Part 1: Percent Change From Baseline in the Frequency of Seizures That Result in Drops (ESC-confirmed) in the Combined Titration and Maintenance Period (T+M) in the…
Congenital Afibrinogenemia · Congenital Hypofibrinogenemia
Primary: Single-dose Pharmacokinetics (PK) of BT524: Terminal Elimination Half-life (t1/2) for Fibrinogen Antigen — 67.9 hours
Diabetes Mellitus, Type 2
Primary: Change in Glycated Haemoglobin (HbA1c) — -1.16; -1.18 Percentage (%) of HbA1c — p=<0.0001
NLRC4-MAS · XIAP Deficiency
Primary: Prevention of Flares — 2.71; NA Weeks
Chronic Hand Eczema
Primary: Number of Participants With IGA-CHE Treatment Success at Week 16 — 47; 7 Participants
Cancer · Lung Cancer · Gastro-intestinal
Primary: Patient Perceptions of Symptom Management - How Well do You Feel Your Oncology Team Understands Your Symptoms (e.g. Nausea, Vomiting, Weight Loss, Etc.)? — 4.5; 4.5…
Asthma
Primary: Annual Asthma Exacerbation Rate (AERR) — 0.42; 1.63 Events per year — p=<0.001
Acute Pain
Primary: Time-weighted Sum of the Pain Intensity Difference (SPID) as Recorded on a Numeric Pain Rating Scale (NPRS) From 0 to 48 Hours (SPID48) SUZ Compared to Placebo — 70.1…
Seasonal Allergic Conjunctivitis
Primary: Ocular Itching Symptom Score — 0.175; 0.085; 0.267; 0.098 score on a scale
Pain
Primary: Safety and Tolerability as Assessed by Number of Participants With Treatment-Emergent Adverse Events (TEAEs) and Serious Adverse Events (SAEs) — 94; 2 Participants
Bunionectomy · Hallux Valgus
Primary: NRS Pain Scores Through 96 Hours Post-surgery — 342.3; 201.3; 377.4 units on a scale*hours — p=<0.00001