N/A N=255 A Patient-Spouse Intervention for Self-Managing High Cholesterol
Hypercholesterolemia
Primary: Low-density Lipoprotein Cholesterol — 123.6; 115.3 mg/dL — p=0.44
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=484 Safety and Immunogenicity of Different Meningitis Vaccine Formulations in Adolescents and Young Adults
Invasive Meningococcal Disease
Primary: Percentages of Subjects With a Seroresponse Against N.Meningitidis Serogroups A,C,W-135,Y, After Receiving Different Formulations of MenABCWY Combination Vaccine. — 90…
Phase 3 N=40 Comprehensive Evaluation of Ischemic Heart Disease Using MRI
Heart Disease, Ischemic · Atherosclerosis, Coronary
Primary: Magnetic Resonance Image Quality Rating — 3.57; 2.55 units on a likert scale — p=<0.001
N/A N=126 Acetic Acid Chromoendoscopy to Judge Gastric Intestinal Metaplasia
Stomach Neoplasms · Metaplasia
Primary: Percent Agreement Between Acetic Acid Chromoendoscopy and Endoscopic Biopsy — 78.5; 94.4; 89.2; 67.1 percentage of lesions
Phase 2 N=234 Topical Metronidazole and Miconazole Co-formulated Vaginal Suppositories for Preventing Vaginal Infections in HIV-seronegative Women
Bacterial Vaginosis · Candidiasis · Trichomoniasis
Primary: Efficacy of Monthly Periodic Presumptive Treatment (PPT) Using Metronidazole With Miconazole Intravaginal Suppositories Versus Matching Placebo Nightly for Five Nights…
N/A N=30 Comparison of Oxygen Delivery Devices for Reversal of Altitude-Induced Hypoxemia in Normal Subjects
Hypoxemia · Hypobaric Hypoxemia
Primary: Return of Oxygen Saturation to Baseline (Sea Level) Values — 6; 8; 10; 4 participants — p=0.3
Phase 2 N=140 Carboplatin and Paclitaxel Combined With Cetuximab and/or IMC-A12 in Patients With Advanced Non-Small Cell Lung Cancer
Recurrent Non-small Cell Lung Cancer · Stage IIIB Non-small Cell Lung Cancer · Stage IV Non-small Cell Lung Cancer
Primary: Progression Free Survival — 3.4; 4.2; 4.0 months
N/A N=1,624 Increasing Evidence-based Clinical Practices in VA
Hand Washing
Primary: Fidelity to the Organizational Model — 3.95; NA; 3.38; NA units on a scale
N/A N=20 Telephone-based Care for OEF/OIF Veterans With PTSD
Post-Traumatic Stress Disorder
Primary: Acceptability to Providers and Patients — 4.7; 3.8; 3.8 units on a scale
Phase 2 N=60 GS-7977 With Ribavirin for Hepatitis C (SPARE)
Hepatitis C
Primary: Participants With Adverse Events — 1; 1; 5; 0 partipants
Phase 4 N=34 A Pharmacodynamic Study With Ticagrelor in African American Patients
Stable Coronary Artery Disease
Primary: Inhibition of the P2Y12 Receptor as Measured by Platelet Reaction Unit (PRU) From VerifyNow™ (a Platelet Function Test Developed by Accumetrics) at 2 Hours After Loading…
Phase 4 N=64 Effect of Molsidomine on the Endothelial (Internal Layer of Blood Vessels) Dysfunction in Patients With Angina Pectoris
Stable Angina Pectoris · Atherosclerosis
Primary: Change Versus Baseline in the Score of the EndoPAT in the Two Groups After One Year of Treatment (Month 12). — 330.60; 164.08 Relative change versus baseline (%)
Phase 2 N=720 A Study to Evaluate the Safety, Tolerability, Immunogenicity and Vaccine-like Viral Shedding of MEDI-534, Against Respiratory Syncytial Virus (RSV) and Parainfluenza Virus Type 3 (PIV3), in Healthy 6 to <24 Month-old Children and in 2 Month-old Infants
Healthy
Primary: Number of Participants With Solicited Symptoms After Dose 1 — 65; 68; 61; 59 participants
Phase 1 N=12 Study to Evaluate the Concentration of Denosumab in Seminal Fluid in Healthy Men After a Single Subcutaneous Dose
Healthy Volunteer
Primary: Maximum Observed Concentration (Cmax) of Denosumab in Seminal Fluid — 100 ng/mL
Phase 4 N=60 Safety and Immunogenicity Among Healthy Children Receiving Fluzone® Quadrivalent Influenza Virus Vaccine
Influenza
Primary: Number of Participants Reporting Solicited Injection-Site or Systemic Reactions Following Vaccination With the 2013-2014 Formulation of Fluzone® Quadrivalent, Influenza…