Phase 3 N=130 A Long-term Study of DE-114 Ophthalmic Solution in Patients With Allergic Conjunctivitis
Allergic Conjunctivitis
Primary: Change in Ocular Itching Score by Visit — -0.6; -0.9; -1.3; -1.7 score
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=20 Effects of Incretins on Human Platelet Function
Inhibition of Platelet Aggregation by Incretins
Primary: Expression of Glucagon Like Peptide -1 (GLP-1) and Gastric Inhibitory Peptide (GIP) Receptors in Normal Human Platelets — 3.73; 4.42 percentage of positive cells — p=0.04
Phase 4 N=26 Effect of Nitrous Oxide (N2O) on Intraocular Pressure in Healthy Volunteers
Glaucoma · Sedation
Primary: Change in Intraocular Pressure During Nitrous Oxide Sedation — 1.05 mmHg (difference in IOP) — p=>0.05
Phase 1 N=32 Safety, Tolerability and Pharmacokinetics of NN1731 in Healthy Volunteers
Congenital Bleeding Disorder · Healthy
Primary: Safety (Physical Examination, Vital Signs, ECG, Haematology, Biochemistry, Urinalysis, Coagulation Factors, Coagulation-related Parameters, Injection Site Tolerability…
Phase 2 N=133 Homeopathic Treatment for Depression in Peri- and Postmenopausal Women
Moderate Depression · Menopausal and Postmenopausal Disorders
Primary: Change From Baseline in 17-item Hamilton Rating Scale for Depression at 6 Weeks. — 9.9; 11.7; 15 Units in Hamilton Scale — p=<0.05
N/A N=153 Effectiveness and Safety Study of LAP-BAND Treatment for Obese Adolescents
Morbid Obesity
Primary: Percent of Subjects Who Attain Clinically Successful Weight Loss of ≥30% Excess Weight Loss (EWL) at 1 Year Post LAP-BAND Implantation. — 49.7 percentage of participants…
Phase 2 N=64 Transversus Abdominis Plane Blocks for Patients Undergoing Robotic Gynecologic Oncology Surgery
Gynecologic Cancer · Post-operative Pain
Primary: 24 Hour Post Operative Opioid Consumption, Converted to Intravenous Morphine Equivalents — 64.9; 69.3 mg
Phase 2 N=30 Medroxyprogesterone +/- Cyclophosphamide & Methotrexate in Hormone Receptor-Negative Recurrent/Metastatic Breast Cancer
Estrogen Receptor-negative Breast Cancer · Progesterone Receptor-negative Breast Cancer · Recurrent Breast Cancer
Primary: Clinical Benefit Rate (CR + PR + SD > 6 Months). — 7.1; 6.3 Percent of Participants
N/A N=1,175 Toronto Thromboprophylaxis Patient Safety Initiative
Venous Thromboembolism
Primary: Percentage of Patients Prescribed Appropriate VTE Prophylaxis — 64; 62; 67; 54 percentage of patients
Phase 3 N=764 A Study to Evaluate the Efficacy and Safety of Intravenous Ceftaroline Versus Intravenous Ceftriaxone in the Treatment of Adult Hospitalised Patients With Community-Acquired Bacterial Pneumonia in Asia
Community-Acquired Bacterial Pneumonia · Lung Infection of Individual Not Recently Hospitalized
Primary: Clinical Cure Rate for Ceftaroline Compared to That for Ceftriaxone at Test of Cure (TOC) in CE Population — 217; 178; 41; 62 Participants
Phase 3 N=442 A Phase 3 Study of Ranolazine in Subjects With Type 2 Diabetes Who Are Inadequately Controlled on Metformin Alone
Type 2 Diabetes Mellitus
Primary: Change From Baseline in Glycosylated Hemoglobin (HbA1c) at Week 24 — 7.86; 7.72; -0.20; -0.37 percent of HbA1c in blood — p=0.306
Phase 2 N=25 Repetitive Transcranial Magnetic Stimulation (rTMS) in the Treatment of Panic Disorder With Comorbid Major Depression
Panic Disorder · Major Depressive Disorder
Primary: Panic Disorder Severity Scale (PDSS) — 6; 1 responders
N/A N=87 Assessment of Energy Balance
Caloric Intake and Energy Metabolism
Primary: ENERGY BALANCE EQUATION, PHASE I, ONE SUB-STUDY — 2360; 2208; -152 kCal
N/A N=102 Pilot Study Assessing Oxidative Stress in Children
Adrenal Insufficiency · Critical Illness
Primary: Pediatric Logistic Organ Dysfunction Score in Critically Ill Children — 15.9 scores on a scale
Phase 2 N=12 Treatment of Depersonalization Disorder With Transcranial Magnetic Stimulation (TMS)
Depersonalization Disorder
Primary: Cambridge Depersonalization Scale (CDS) — 6 responders (>50% reduction in CDS score)