N/A N=84 Bundling and Unbundling the Laparoscopic Electrosurgery Cord With the Camera Cord
Fatigue
Primary: Histologic Thermal Injury to Umbilical Port Site Skin — 24; 13 participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=664 MarginProbe, a Device for Intraoperative Assessment of Margin Status in Breast Conservation Surgery
Breast Cancer
Primary: The Primary Effectiveness Endpoint is a Measure of Intraoperative Success in Addressing Positive Margins as Detected by Permanent Pathology)by Additional Oriented Tissue…
Phase 1 N=18 Investigation of the Effect of Food on the Bioavailability of a 25 mg Empagliflozin Tablet as Well as Assessment of Dose Proportionality Between 10 mg and 25 mg Empagliflozin Tablets Under Fasting Conditions.
Healthy
Primary: Area Under the Curve 0 to Infinity (AUC0-∞) — 5380; 4520; 2280 nmol*h/L
N/A N=274 Comparison of Glycemic Control in Obese Diabetics Using Three Different Pen Needles
Diabetes Mellitus, Type 1 · Diabetes Mellitus, Type 2
Primary: Glycemic Control as Measured by HbA1c (4 mm vs. 8 mm) — 7.59; 7.46; 7.63; 7.59 HbA1c (%)
Phase 3 N=100 Characterisation of 24-hour FEV1-time Profiles of Inhaled BI 1744 CL and Inhaled Foradil in Patients With Chronic Obstructive Pulmonary Disease
Pulmonary Disease, Chronic Obstructive
Primary: FEV1 Area Under Curve 0-12 h (AUC 0-12h) Response After Six Weeks of Treatment — -0.022; 0.150; 0.152; 0.136 Liter — p=<0.0001
Phase 4 N=22 Study to Evaluate Effect of Belatacept on Pharmacokinetics of Inje Cocktail in Healthy Volunteers
Transplant Rejection
Primary: Adjusted Geometric Mean Maximum Drug Concentration (Cmax) of Midazolam With and Without the Coadministration of Belatacept - Pharmacokinetic (PK) Evaluable Population…
N/A N=44 Evaluation of Stenfilcon A Versus Etafilcon A
Myopia
Primary: Participant's Subjective Rating of Comfort (Questionnaire) — 92; 91; 96; 93 units on a scale
Phase 2 N=85 Safety and Benefit Study of Droxidopa to Treat Patients With Intradialytic Hypotension
Intradialytic Hypotension
Primary: Change in Average Mean Arterial Blood Pressure During Hemodialysis — -0.12; 1.95; 1.60 mmHg — p=0.693
N/A N=3,031 Early Versus Delayed Timing of Intervention in Patients With Acute Coronary Syndromes
Unstable Angina · Myocardial Infarction
Primary: Composite of Death, Myocardial (re-) Infarction, or Stroke — 153; 163 participants — p=0.15
N/A N=16 Use of Two Deep Brain Stimulation (DBS) Electrodes to Treat Post-Traumatic Tremor
Multiple Sclerosis
Primary: Fain-Tolosa-Marin Tremor Rating Scale (TRS) Change Score for Both VIM and VO ON (Baseline Minus 6 Months Post-implant) — -17.6 units on a scale — p=.026
Phase 4 N=20 Effectiveness of Escitalopram in Preventing or Reducing Depressive Symptoms in People Receiving Interleukin-2 Treatment
Depression
Primary: Number of IL-2 Treatments Tolerated — 18.4; 19.8 IL-2 treatments
Phase 3 N=636 Comparison Between Rectal & Sublingual Misoprostol Before Caesarian Section To Reduce Intra & Post-Operative Blood Loss
Postpartum Hemorrhage
Primary: Intraoperative Blood Loss — 357.8; 641.7; 457.5 millilitres
N/A N=32 Evaluation of a Sensory Enrichment Multimodal Device (SEMD) on Physical Therapy Patients With Disequilibrium
Vestibular Diseases · Labyrinth Diseases · Ear Diseases
Primary: Assessment of the Efficacy of the SEMD Device in Improving Vestibular Function Was Evaluated With Change in Pre Test to Post Test 1 Sensory Organization Test (SOT)…
Phase 1 N=259 Contact Sensitization Potential of 828 Ointment
Healthy Volunteers
Primary: Number of Participants That Exhibited a Score Less Than 1.5 on the Jordan-King Scale — 205 participants
Phase 2 N=211 Bevacizumab and Oxaliplatin Combined With Irinotecan or Leucovorin and Fluorouracil in Treating Patients With Metastatic or Recurrent Colorectal Cancer
Colorectal Cancer
Primary: Objective Response Rate — 0.33; 0.38; 0.49 proportion