65,437 trials
Type B Aortic Dissection
Primary: All-cause Mortality Incidence Through 30 Days Post-treatment — 5 participants — p=.006
Leishmaniasis, Cutaneous
Primary: Number of Participants Who Obtained Final Clinical Cure of Index Lesion — 9; 13 Participants
Seasonal Allergic Rhinitis
Primary: Change From Baseline in Average Daily Subject Reported AM and PM Reflective Total Nasal Symptom Scores (rTNSS) Over the 2-week Double-blind Treatment Period — -1.63…
Rheumatoid Arthritis
Primary: Percentage of Participants Achieving Functional Remission Determined by Hannover Functional Ability Questionnaire (FFbH) at Week 26 — 36.4 percentage of participants
Hyperlipidemia · Diabetes · Hypertension
Primary: Metabolic Syndrome (MetS) — 85.2; 71.2 percentage of participants
Dupuytren's Disease
Primary: The Measured Change in Volume of the Cord by MRI Before and After XIAFLEX Injection and Manual Manipulation. — 482 mm^3 — p=<0.0013
Bladder Cancer · Muscle-invasive Bladder Cancer
Primary: Number of Patients Achieving Pathologic Response — 49 percentage of pathologic responders
Degenerative Disc Disease
Primary: Participants With Improved Patient Function — 7; 6 participants — p=1.0
Hepatic Impairment · Healthy
Primary: Area Under the Plasma Concentration-time Curve (AUC) of SSP-004184 — 254327.7; 443053.5; 288579.6; 410414.3 ng*h/ml
Postoperative Hemorrhage
Primary: Time to Hemostasis — 2.2; 4.4 minutes — p=0.004
Anemia
Primary: Hemoglobin Concentration at Monthly Intervals — 11.27; 11.26; 11.19; 11.14 g/dL
Acute Low Back Pain
Primary: Pain Intensity Difference (PID) Between Pre-dose Baseline and 8hours After First Application — -1.049; -1.428; -2.252; -2.410 units on a scale — p=<0.0001
Gingival Diseases
Primary: Keratinized Tissue Width — 4.42; 2.92 mm — p=<0.0001
Polycystic Ovary Syndrome
Primary: Mu-opioid Binding Potential Measured in Left Nucleus Accumbens — 1.95; 1.65; 1.53 ratio — p=0.143
Bowel Preparation Prior to Endoscopic, Radiological and Other Examinations as Well as to Surgical Procedures Which Require Empty Bowel.
Primary: Percentage of Participants With Successful Colon Cleansing — 94.29; 91.43 percentage of participants — p=<0.001