Phase 3 N=440 Efficacy of Bromfenac Ophthalmic Solution in Patients Undergoing Cataract Surgery
Pain · Inflammation · Cataract
Primary: Ocular Inflammation — 108; 53 eyes
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=41 Tanespimycin in Treating Patients With Inoperable Locoregionally Advanced or Metastatic Thyroid Cancer
Recurrent Thyroid Cancer · Stage IV Follicular Thyroid Cancer · Stage IV Papillary Thyroid Cancer
Primary: Proportion of Patients Who Have Remained on Treatment and Progression-free at Least One Year After Start of 17-AAG (Tanespimycin) — 5.9; 12.5 percentage of participants
N/A N=18 Immediate Loading Of Dental Implants: A Pilot Clinical Study
Dental Implantation
Primary: Patient Satisfaction With the Immediate Loading Protocol — 40.3 millimeters
Phase 2 N=163 Extension Study Evaluating Antibody Persistence and Safety, Tolerability and Immunogenicity of Booster Doses of Novartis rMenB±OMV NZ Vaccine in Healthy UK Children Who Previously Received One or Four Doses of the Same Vaccine
Meningococcal Disease
Primary: Persistence of Geometric Mean Antibody Titers in Children (Who Previously Received 4 Doses of Men B Vaccine), at 40 Months of Age. — 3.24; 5.34; 4.25; 5.11 Titers
Phase 3 N=6,100 Safety, Tolerability, and Immunogenicity of the Adjuvanted Trivalent Subunit Influenza Vaccine and the Non-Adjuvanted Trivalent Subunit Influenza Vaccine Compared to the Non-Adjuvanted Trivalent Split Influenza Vaccine in Children 6 to < 72 Months of Age
Influenza Disease
Primary: Comparison of Antibody Responses of aTIV With TIV and Comparator TIV in Terms of Geometric Mean Titers (GMTs) Against Homologous Strains — 28; 24; 27; 1537 Titers
Phase 4 N=30 Niacin and Endothelial Function in Early CKD
Chronic Kidney Disease
Primary: Change in the Flow Mediated Dilation From Baseline — 3.07; 1.37 absolute percent change — p=0.71
Phase 3 N=1,186 Comparison of Treatment Effect of Chemotherapy With Panitumumab to Chemotherapy Alone
Metastatic Colorectal Cancer
Primary: Progression-free Survival (PFS) — 5.9; 3.9; 5.0; 4.9 months — p=0.0036
Phase 4 N=76 Carbetocin Versus Oxytocin and Hemodynamic Effects
Effects of; Anesthesia, in Pregnancy
Primary: Cardiac Output — 96; 82; 43 percentage change in cardiac output
N/A N=884 Evaluation of Capsule Endoscopy With PillCam® COLON 2 in Visualization of the Colon
CRC Screening
Primary: Sensitivity and Specificity of PillCam Platform With the PillCam COLON 2 Capsule in Detecting Patients With Polyps ≥6 mm Where OC Considered as the Gold Standard…
Phase 3 N=846 A Safety and Efficacy Study of Ciclesonide Nasal Aerosol in Subjects 6-11 Years With Perennial Allergic Rhinitis (PAR).
Perennial Allergic Rhinitis · PAR
Primary: The Change From Baseline in Average Daily Subject-reported AM and PM Reflective Total Nasal Symptom Scores (rTNSS) Averaged Weekly Over the First 6 Weeks of the…
Phase 3 N=583 Trial With Cetuximab in Maintenance Therapy After Platinum Based Chemotherapy in First Line Treatment of Non-small Cell Lung Cancer (NSCLC)
Non-Small Cell Lung Cancer (NSCLC)
Primary: Overall Survival (OS) Time — 16.1; 15.5 months
Phase 2 N=697 Safety and Immunogenicity of a Group B Streptococcus Vaccine in Non Pregnant and Pregnant Women 18-40 Years of Age
Streptococcal Infections
Primary: The Percentages of Non-pregnant Subjects With Antibody Concentrations Above a Defined Threshold at One Month After the Second Vaccination. — 91; 37; 91; 32 percentage of…
Phase 3 N=15 Sitagliptin Regulation of Intestinal and Hepatic Lipoprotein Particle and Hepatic Glucose Production in Humans
Hyperlipidemia
Primary: Apolipoprotein B48 Production Rate After Acute Oral Administration of 100mg Sitagliptin (Compared to Placebo) — 122.9; 60.6 ug/kg/day
Phase 3 N=1,375 A Study of DTaP-IPV-Hep B-PRP-T Vaccine Given With Prevenar™ and Rotarix™ in Healthy Latin American Infants
Diphtheria · Tetanus · Whooping Cough
Primary: Geometric Mean Titers (GMTs) of Anti-Hepatitis B Before and After 3 Dose Primary Vaccination With Either DTaP-IPV-Hep B-PRP~T Batch A, B, or C, or Infanrix Hexa™ — 4.02…
Phase 3 N=62 Study of Aripiprazole (Abilify) Versus Placebo in Children With Subsyndromal Bipolar Disorder
Bipolar Disorder
Primary: Young Mania Rating Scale (YMRS) — 24.8; 21.6 Scores on a scale