Phase 4 N=101 Comparing Effectiveness of CSE Versus DPE for Labor Analgesia
Labor Pain
Primary: Number of Participants With the Presence of Any of the Five Block Quality Components (or More Than One) — 16; 13 Participants — p=0.486
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=39 Nasal Spray Study in Sjogren's Dry Eye Disease
Sjogren's Syndrome · Dry Eye
Primary: Mean Change in Cornea Staining — -1.78 units on a scale
Phase 4 N=463 To Evaluate Real-World Effectiveness of Fluticasone Furoate/Umeclidinium Bromide/Vilanterol (FF/UMEC/VI) in a Single Inhaler (Trelegy Ellipta) in Participants With Symptomatic COPD
Pulmonary Disease, Chronic Obstructive
Primary: Change From Baseline in COPD Assessment Test (CAT) Score at Week 12 — -6.8 Scores on a scale
Phase 4 N=229 Apixaban for the Acute Treatment of Venous Thromboembolism in Children
Venous Thromboembolism
Primary: Percentage of Participants With Composite of Major and Clinically Relevant Non-Major (CRNM) Bleeding — 1.3; 1.4 percentage of participants
Phase 4 N=175 Amlodipine Versus Nifedipine ER for the Management of Postpartum Hypertension
Hypertension in Pregnancy
Primary: Length of Stay — 73.5; 72.0 hours
Phase 4 N=519 Acetazolamide in Decompensated Heart Failure With Volume OveRload (ADVOR)
Acute Decompensated Heart Failure · Volume Overload
Primary: Successful Decongestion — 79; 108 Participants
Phase 4 N=44 Arginine Supplementation to Improve Cardiovascular and Endothelial Function After NSAID Treatment
Healthy
Primary: Log Reactive Hyperaemic Index — 0.003; 0.095 LnRHI (Log Reactive hyperaemic index)
Phase 4 N=834 Early Administration of Steroids in the Ambulance Setting
Asthma in Children
Primary: Hospital Admission — 57; 208 Participants
Phase 4 N=114 Effect of Perioperative Gabapentin on Postoperative Opioid Requirements
Postoperative Pain
Primary: Opioid Prescription at Discharge — 40; 40; 19; 15 Participants
Phase 4 N=15 Effects of Interleukin (IL)- 4R-alpha Inhibition on Respiratory Microbiome and Immunologic Correlates in Severe Asthma
Asthma
Primary: Changes in Alpha-diversity of Respiratory Microbiota — 0.13 Shannon's index
Phase 4 N=200 Diabetes Remote Intervention to improVe Use of Evidence-based Medications
Cardiovascular Diseases · Diabetes
Primary: Number of Patients With Prescriptions of SGLT2i or GLP1-RA at Any Time — 81; 47 Participants
Phase 4 N=21 A Pilot Study Comparing Anti-Inflammatory Effects Of TXA Versus EACA In Pediatric Congenital Heart Surgery
Pediatric Cardiac Surgery · Complication of Extracorporeal Circulation
Primary: Inflammatory Markers/Cytokines — 1.5; 2.1; 1.6; 2.2 pg/dl
Phase 4 N=277 Effectiveness and Safety of Combination of Amlodipine and Zofenopril in Hypertensive Patients Versus Each Monotherapy
Hypertension
Primary: Change in Mean Sitting Diastolic Blood Pressure (DBP) Between Visit 2 (Week 0) and Visit 4 (Week 8) — -13.5 mmHg — p=< 0.001
Phase 4 N=60 Efficacy and Safety of CAZ-AVI in the Treatment of Infections Due to Carbapenem-resistant G- Pathogens in Chinese Adults
Urinary Tract Infection · Acute Pyelonephritis · Hospital Acquired Pneumonia
Primary: Percentage of Participants With Clinical Cure at Test of Cure (TOC) Visit - Microbiologically Modified Intent-to-Treat (mMITT) Analysis Set — 59.3; 25.9 Percentage of…
Phase 4 N=28 Afrezza With Basal Combination (ABC): Afrezza® Combined With AID Pump or Insulin Degludec in Adults With Type 1 Diabetes
Type 1 Diabetes
Primary: Change in HbA1c — 0.32; 0.35; 0.52 percent of glycated hemoglobin