65,437 trials
Bipolar I Disorder
Primary: Young Mania Rating Scale (YMRS) — -22.6; -15.4 scores on a scale
Depression · Palliative Care · Cancer
Primary: Days to Remission of Depression — 10.3; 8.1 Days
Cocaine Dependence · Cocaine Abuse · Cocaine Addiction
Primary: Timeline Followback Interview (TLFB) — 0.11; 0.63 grams of cocaine used — p=<0.25
Breast Reconstruction
Primary: Local Complications — 15.0; 21.6; 11.1; 10.7 Percentage by Patient
Bipolar I Disorder
Primary: Young Mania Rating Scale (YMRS) — -18.3 scores on a scale
Chronic Obstructive Pulmonary Disease (COPD)
Primary: Spirometry Results: FEV1 (L) — 1.4 Liters
Abscess · Wound Infection · Surgical Site Infection
Primary: Early Clinical Efficacy — 285; 288; 86; 80 participants
First or Second Line HER2-negative Breast Cancer · Metastatic Disease Without Bone Metastasis
Primary: Number of Participants With Progression Free Survival (PFS) — 9; 19; 6; 10 Participants
Pulmonary Disease, Chronic Obstructive
Primary: Change From Baseline (BL) in Weighted Mean (WM) 0-6 Hour Forced Expiratory Volume in One Second (FEV1) Obtained Post-dose at Day 14 of Each Treatment Period (TP) by…
Extensive Stage Small Cell Lung Cancer · Lung Metastases · Malignant Pleural Effusion
Primary: Progression-free Survival Rate at 12 Weeks — 26 percentage of participants
Hemophilia A
Primary: Annualized Number of All Bleeds — 57.7; 4.9 Bleeds per year per participant — p=0.0001
Irritable Bowel Syndrome With Constipation
Primary: Overall Responder Rate — 13.8; 7.8 percentage of participants — p=0.029
Major Depressive Disorder
Primary: Change From Baseline in MADRS Total Score After 8 Weeks of Treatment. — -11.70; -17.23; -18.79; -21.15 units on a scale — p=<0.0001
Epilepsies, Partial
Primary: PCH(T), ITT — -42.90; -38.20; -28.70 percentage of change — p==0.003
Infertility
Primary: Serum Progesterone (P4) Level in the Morning of the Day of Human Chorionic Gonadotrophin (hCG) Administration — 0.69; 0.72; 0.54; 0.89 ng/ml — p=0.003