N/A N=10 WallFlex Biliary Post Liver Transplant IDE Pilot
Anastomotic Biliary Stricture Post Orthotopic Liver Transplant
Primary: Stricture Resolution at the Time of Stent Removal. — 9; 1 participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=16 The Role of Substance P on Perception of Breathlessness During Resistive Load Breathing
Chronic Obstructive Pulmonary Disease
Primary: Intensity of Breathlessness — 80.8; 77.9 units on a scale
Phase 3 N=299 Efficacy and Safety Study of Linagliptin (5 mg Administered Orally Once Daily) Over 24 Weeks, in Drug naïve or Previously Treated Type 2 Diabetic Patients With Insufficient Glycaemic Control
Diabetes Mellitus, Type 2
Primary: HbA1c Change From Baseline at Week 24 — -0.18; -0.68 % of HbA1c — p=<0.0001
Phase 2 N=1 Rollover Study of Weekly Paclitaxel (BMS-181339) in Patients With Advanced or Recurrent Esophageal Cancer
Esophageal Cancer
Primary: Number of Adverse Events (AEs) Per Participant — 32 adverse events
N/A N=546 A Randomized Trial of Vaccine Adherence in Young Injection Drug Users
Medication Adherence · Substance Abuse, Intravenous · Risk Behavior
Primary: Vaccine Series Completion — 16; 20; 8; 10 participants
Phase 3 N=238 Safety and Efficacy of Ziprasidone in Children and Adolescents With Bipolar I Disorder (Manic or Mixed)
Bipolar Disorder
Primary: Change From Baseline in Young Mania Rating Scale (YMRS) Score at Week 4 — 26.2; 27.0; -13.8; -9.9 units on a scale — p=0.0005
N/A N=10 HOP-2A - Intratesticular Hormone Levels
Healthy · Male Infertility · Prostate Disease
Primary: Intratesticular Hormones in Normal Men — 486; 3.0; 3.7; 0.20 ng/mL
Phase 2 N=112 Lapatinib in Combination With Vinorelbine
Cancer
Primary: Progression Free Survival (PFS) in the Randomized Phase — 6.2; 6.2 months
Phase 4 N=40 A Randomized Double-Blind Study Testing the Effects of Pregabalin on Diabetic Neuropathy
Diabetic Neuropathy
Primary: Assessing the Change in Resting Blood Pressure Upon Treatment of Pregabalin vs. Placebo in Patients With Diabetes and Peripheral Neuropathy. — -7.63; -8.98; -4.41; -4.93…
Phase 2 N=26 Oral Topotecan to Treat Recurrent or Persistent Solid Tumors
Tumors
Primary: Maximum Tolerated Dose (MTD) of Single Agent Metronomic Oral Topotecan — 1.0 mg/day
Phase 4 N=81 Effects of Neupro on Cardiovascular Observations in Patients With Restless Legs Syndrome
Restless Legs Syndrome
Primary: Change From Baseline in the Number of Elevations of Systolic Blood Pressure (BP) During the Night That Are Associated With Periodic Limb Movements (PLMs) at the End of…
N/A N=5,392 Impact of Body Weight on the Immediate Health of the Pediatric Population
Childhood Obesity
Primary: Diagnosis of Infectious Disease — 900; 1067 Participants — p=.026
Phase 2 N=50 Pharmacological Intervention Project (Fluoxetine)
Alcoholism · Depression
Primary: Alcohol Use Behaviors — 1.56; 1.73 standard drink (14 gr. alcohol) — p=.05
Phase 2 N=197 Study of Dose-dense Adriamycin Plus Cytoxan (AC) Followed by Either ABI-007 (Abraxane) or Taxol With Bevacizumab as Adjuvant Therapy for Patients With Breast Cancer
Breast Cancer
Primary: Participants With Treatment-Emergent Toxicities With a Frequency >=20% at 3 Months Post Chemotherapy — 65; 74; 65; 77 participants — p=0.641
Phase 2 N=215 Phase II Dose-ranging Study of APD421 in PONV
Postoperative Nausea and Vomiting
Primary: Post-operative Nausea or Vomiting — 37; 28; 20; 30 participants