6,678 trials
Stage 2 Diastolic Hypertension
Primary: The Change From Baseline in Trough Seated Diastolic Blood Pressure at Week 6. — -8.0; -17.2; -13.3; -12.0 mm HG
Psoriasis · Psoriatic Arthritis
Primary: Percentage of Participants With Psoriatic Arthritis (PsA) Based on Physical Examination, Medical History and Laboratory Results — 30.0 Percentage of participants
Renal Transplant
Primary: Dose-Normalized Area Under the Concentration-time Curve From Time 0 to 12 Hours (AUC0-12h) at Steady State — 51.73; 50.58 ng*hr/mL/mg — p=0.486
Glaucoma
Primary: Mean Intraocular Pressure (IOP) at 8:00 PM — 17.1; 17.7 mm Hg
Neuropathic Pain
Primary: Change From Baseline in the Average Pain Over the Last 24 Hrs on the Brief Pain Inventory (BPI) Scale — -1.2 units on a scale
Excessive Sleepiness
Primary: Percentage of Patients With at Least Minimal Improvement From Baseline in the Clinical Global Impression of Change (CGI-C) Rating as Related to Late Shift Sleepiness at…
Chronic Kidney Disease · Secondary Hyperparathyroidism · Hemodialysis
Primary: The Number of Participants Who Achieve a Mean Intact Parathyroid Hormone (iPTH) Value Between 150 to 300 pg/mL During the Evaluation Period (Weeks 21 to 28). — 30; 16…
Cardiovascular Diseases · Metabolic Syndrome X · Atherosclerosis
Primary: Change in Nitric Oxide Formation From Baseline to 3 Months — 27.6; 27.0; 31.4; 25.7 ng/mL
Heart Failure · CHF
Primary: Time Required for the Pulmonary Artery Occlusion Pressure (PAOP) to be Maintained at a Value of Less Than or Equal to 18 mmHg for at Least Four Consecutive Hours (+/- 30…
Urinary Tract Problem
Primary: Smooth cLMA Removal Condition (Score 1) — 86; 40 percentage of participants — p=<0.05
Heart Failure · Ventricular Dysfunction, Left
Primary: Composite Value of 3 Variables After 9 Months: Cardiovascular Death (Days Alive), Cardiovascular Hospitalization (Days Out of Hospital), Heart Failure Symptoms (Symptom…
Cardiovascular Diseases · Atherosclerosis · Myocardial Infarction
Primary: Change in Nitric Oxide Formation From Baseline to 3 Months. — 10.0; 11.2; 10.0; 11.0 ng/mL
Hip Fracture
Primary: 25-hydroxyvitamin D3 (25-OHD) — 53.5; 58.4; 46.7; 84.5 nmol/L
Echocardiography
Primary: The Frequency of Serious Adverse Reactions (SAR)'s Among Subjects Who Receive Optison (Causally Related to the Product)During Contrast Enhanced Echocardiography in…
ADHD
Primary: DSM-IV ADHD Rating Scale (AISRS) Score Change — -17.5; -10.6; -6.9 Units on a scale