Clinical Trial Search

Primary: Whole Mouth Lobene Modified Gingival Index Between the Brushing Only Group and the Brushing + Flossing Group [30 Days] Units on the MGI Scale — 1.84; 1.73 units on a…

Primary: Feasibility of Randomizing a Cohort of Participants Meeting the Inclusion and Exclusion Criteria of the Study — 21 participants

Primary: Percentage of Participants Who Experienced Seizure Freedom for 26-weeks During the Maintenance Phase — 79.4; 83.7 Percentage of Participants

Primary: Change in Average Pain Scores From Baseline to Week 15/End of Treatment (EOT) — -2.22; -1.73; -1.30; -1.85 Scores on a Scale

Primary: Percentage of Participants With Abnormal Clinically Significant Vital Signs in Cohort 1 — 0.8; 1.6; 9.5; 10.5 percentage of participants

Primary: Mean Change From Baseline in Short Form-McGill Pain Questionnaire (SF-MPQ): Sensory and Affective Scores, From Baseline to Week 48. — -10.5; -8.1; -9.0; -9.8 Scores on a…

Primary: Mean # Participants Who Had Hospitalizations or ED Visits Compared to Usual Care in a High Risk Group of Adults ≥ 60 Years of Age With Mixed Chronic Disease. — 65; 59…

Primary: Number of Participants With Sedation Success — 18; 24; 18; 21 Participants

Primary: Time to Progression — 2.3; 7.2 Months

Primary: Percent Change in Number of Rectal Aberrant Cryptic Foci (ACF) as Measured by Magnification Chromoendoscopy — 8.4; -13.3; -8.8; -8.6 percent change in number of ACF…

Primary: Participants Indicating "I do Not Know" on Depth Questionnaire. — 7; 4; 4; 4 participants

Primary: Co-primary Endpoint- Percentage of Participants Achieving Greater Than or Equal to 5% Weight Loss From Baseline to Week 52 — 37.5; 44.7; 16.1 percentage of participants…

Primary: Change From Baseline to Day 1&2 in Wake After Sleep Onset (WASO) — 85.0; 86.6; 92.3; 76.5 minutes — p=<0.0001

Primary: Monocular Visual Acuity on LogMAR Scale — -0.065; -0.038 logMAR

Primary: Participant BMI — 36.0; 36.4; 36.3; 36.8 kg/m^2 — p==0.51