12,372 trials
Infections, Meningococcal
Primary: Number of Subjects With Vaccine Response to Meningococcal Antigens — 472; 148; 625; 204 Participants
Chronic Obstructive Pulmonary Disease
Primary: Change From Baseline in Forced Expiratory Volume (FEV1) Area Under the Curve (AUC) 0-24h — 0.1846; 0.2028 Liters — p=0.415
Parkinson's Disease · Dyskinesia
Primary: Change From Baseline in Diary-Based On-Time Without Dyskinesia at Week 12 — 1.6; 1.9; 1.7; 1.8 hours/day
Diabetes · Diabetes Mellitus, Type 2
Primary: Change From Baseline in HbA1c (Glycosylated Haemoglobin) — -1.54; -0.92 percentage of glycosylated haemoglobin — p=< 0.0001
Hypogonadism
Primary: Incidence of Adverse Events as a Measure of Safety of QuickShot™ Testosterone (QST) Administered Subcutaneously (SC) Once Each Week to Adult Males With Hypogonadism…
Acute Heart Failure
Primary: Percentage of Participants With Confirmed Cardiovascular (CV) Death Through Day 180 — 8.7; 8.9 Percentage of participants — p=0.3857
Asthma
Primary: Time to Asthma Exacerbation (Mean Number of Exacerbations/Person-year) — 0.37; 0.42 event per person-year — p=0.31
Attention Deficit Disorder With Hyperactivity
Primary: Change From Baseline in Attention Deficit Hyperactivity Disorder Rating Scale, Version 5 (ADHD-RS-5) Total Score — -14.2; -12.1 units on a scale
Opioid Use Disorder · Opioid-related Disorders
Primary: Participants With Treatment-Emergent Adverse Events (TEAE) During the Treatment Period — 302; 145; 172; 61 Participants
Chronic Allergic Conjunctivitis
Primary: Ocular Itching Post-CAC (Conjunctival Allergen Challenge) at Visit 6 — 1.68; 2.66 units on a scale
Deep Vein Thrombosis · Venous Thrombosis · Postphlebitic Syndrome
Primary: Cumulative Incidence of Post-Thrombotic Syndrome (Villalta Scale) — 157; 171 Participants — p=0.56
Type 1 Diabetes Mellitus
Primary: Adjusted Mean Change in HbA1c From Baseline at Week 24 — -0.45; -0.47; -0.03 Percentage of hemoglobin — p=<0.0001
Hepatitis C
Primary: Percentage of Participants With Sustained Virologic Response (SVR12) — 92.6; 75.0 Percentage of participants
Atrial Fibrillation · Atrial Flutter
Primary: Occurrence of Post-operative Atrial Fibrillation Requiring Treatment After Open Heart Surgery — 50; 56; 58; 48 Participants
Arthritis, Rheumatoid
Primary: Initial Period: Primary Endpoints Were Standard Laboratory Safety Data (Chemistry, Hematology, Etc.) and Adverse Event (AE) Reports — 991; 2963; 3954; 159 Number of…