Phase 4 N=65 Prasugrel Re-load Strategies
Coronary Artery Disease
Primary: PRI Levels at 4 Hours — 28.8; 11; 2.8 percentage of platelet reactivity
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=3,647 Safety, Tolerability and Immunogenicity of Two Doses of Adjuvanted Monovalent Influenza Vaccine Administered to Healthy Adult and Elderly Subjects
Pandemic Influenza Disease
Primary: Number of Subjects With at Least One Reactogenicity Sign After Two Doses of the Adjuvanted Pandemic Influenza Vaccine. — 1755; 502; 237; 78 Participants
Phase 4 N=75 Study of 6(S)-5-MTHF Among Selective Serotonin Reuptake Inhibitor-Resistant Outpatients With Major Depressive Disorder
Depression
Primary: The 17-item Hamilton Depression Scale (HAM-D-17) — -7.4; -4.4; -3.8; -1.7 Scores on a scale — p=.05
Phase 4 N=55 Ablation of the Pulmonary Veins for Paroxysmal Afib
Paroxysmal Atrial Fibrillation
Primary: Number of Participants With Successful Pulmonary Vein Isolation — 53 participants
Phase 2 N=392 A Dose Ranging Trial of 4 Doses of Indacaterol Delivered Via TWISTHALER® Device in Adult and Adolescent Patients With Persistent Asthma
Asthma
Primary: The Mean Change From Baseline to 24 Hour Post-dose (Trough) Forced Expiratory Volume in 1 Second (FEV1) — 0.039; 0.054; 0.124; 0.166 liters
N/A N=66 Comparing Use of the Glidescope Cobalt to Direct Laryngoscopy in Infants
Intubation
Primary: Time to Tracheal Intubation — 21.4; 22.6 seconds
Phase 4 N=25 Comparison of Insulin Detemir and Insulin Aspart in 2 Separate Injections Twice Daily to Extemporaneous Mixing Injection Regimen Twice Daily - The Paediatric Mixing Trial
Diabetes · Diabetes Mellitus, Type 1
Primary: Glycosylated Haemoglobin A1c (HbA1c) — 8.00; 7.77; 7.63; 8.15 percentage of total haemoglobin — p=0.001
Phase 2 N=37 Degarelix as Second-Line Hormonal Treatment After Prostate-specific Antigen (PSA)-Failure in GnRH Agonist Treated Patients With Prostate Cancer
Prostate Cancer
Primary: Participants' Response in Prostate-Specific Antigen (PSA) Level at Three Months As Compared to Baseline — 16.67; 33.33; 83.33; 66.67 percentage of participants
Phase 2 N=80 Avastin/Radiation (XRT)/Temozolomide (Temodar) Followed by Avastin/Temodar/Topotecan for Glioblastoma
Malignant Glioma · Glioblastoma · Gliosarcoma
Primary: 6-month Progression-free Survival — 88.8 percentage of participants
Phase 3 N=163 Long Term Safety and Tolerability of NVA237 Versus Tiotropium in Japanese Patients
Chronic Obstructive Pulmonary Disease
Primary: Number of Participants With Adverse Events, Serious Adverse Events or Death — 102; 33; 16; 6 participants
Phase 4 N=36 Efficacy of Omalizumab in Adults (18-60 Years of Age) With Moderate-Severe, Persistent Allergic Asthma, Despite Receiving Inhaled Corticosteroids and Long Acting Beta-agonists
Allergic Asthma
Primary: Change From Baseline in Total Subepithelial Eosinophils at the End of Week 78 (End of Treatment) — -5.807; -5.890; 1.555; -5.626 cells/mm^2
Phase 2 N=568 A Dose Ranging Trial of 4 Doses of Indacaterol Delivered Via the TWISTHALER® Device in Patients With Chronic Obstructive Pulmonary Disease (COPD)
COPD
Primary: The Mean Change From Baseline to 24 Hour Post-dose (Trough) Forced Expiratory Volume in 1 Second (FEV1) — 0.051; 0.073; 0.076; 0.121 liters
Phase 1 N=20 A Phase 1 Study of MP-424, Peginterferon Alfa 2b, and Ribavirin in Hepatitis C
Hepatitis C
Primary: Cmax (Maximum Observed Concentration in Plasma) of MP-424 — 1.62; 1.45; 3.96; 3.06 μg/mL
Phase 3 N=1,200 Safety and Immunogenicity of 3 Lots of Cell-derived Subunit Influenza Vaccine as Compared to 1 Lot to Egg-derived Subunit Influenza Vaccine in Healthy Adults (>=18 to <=60)
Influenza
Primary: Geometric Mean Titers After One Dose of Cell Culture-derived or the Egg-derived Influenza Vaccine in Adult Subjects — 12; 15; 16; 14 Titers
Phase 2 N=43 Dasatinib in Treating Patients With Previously Treated Malignant Mesothelioma
Malignant Mesothelioma
Primary: 24 Week Progression Free Survival — 23 percentage of participants