Phase 2 N=150 iCare Stress Management e-Training for Dementia Family Caregivers
Alzheimer's Disease · Dementia
Primary: Perceived Stress Scale — 15.83; 16.41 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=39 Quantitative Electroencephalogram (QEEG) Predictors of Response to Psychotherapy Versus Antidepressant Treatment in Depression
Major Depressive Disorder
Primary: Hamilton Depression Rating Scale (HAM-D-17) Scores — 10.64; 13.78 units on a scale
Phase 2 N=509 Comparison Of 6 CP-690,550 Doses Vs.Placebo, Each Combined With Methotrexate, For The Treatment Of Rheumatoid Arthritis
Arthritis, Rheumatoid
Primary: Percentage of Participants Achieving American College of Rheumatology 20% (ACR20) Response at Week 12 — 47.14; 55.88; 56.34; 58.11 percentage of participants
Phase 3 N=324 13-valent Pneumococcal Conjugate Vaccine Study in Adults => 50 Years of Age in Mexico
Pneumococcal Infections
Primary: Serotype-Specific Pneumococcal Opsonophagocytic Activity (OPA) Geometric Mean Titers (GMTs) 1 Month After Vaccination — 120; 84; 88; 89 titer
N/A N=197,502 A Study to Evaluate the Safety of FluMist in Healthy Children and Healthy Adults
Healthy
Primary: Rates of Medically Attended Events (MAEs) Associated With a Significant Increased Risk in FluMist Recipients Compared to Rates in Within Cohort, Unvaccinated, and TIV…
N/A N=682 Temodal (Temozolomide) Post Marketing Surveillance Protocol (Study P05557AM2)
Glioblastoma · Glioma · Astrocytoma
Primary: Number of Participants Experiencing Adverse Events (AEs) — 324 participants
N/A N=20 Merits of Performing a Modified Template Retroperitoneal Lymph Node Dissection
Cancer of the Urinary Tract
Primary: Number of Participants With Pathologically Proven Lymph Node Metastasis — 1 participants
Phase 2 N=1 Effect of 2-h Infusion of ON 01910.Na in Ovarian Cancer Patients
Ovarian Cancer
Primary: Progression Free Survival — 54 day
N/A N=3,929 Computer-Assisted Self-Interviews and Health Screening in the Pediatric Emergency Department
Gonorrhea · Chlamydia
Primary: Gonorrhea and Chlamydia Testing in the Pediatric ED — 9.7; 9.3; 17.8; 12.4 percentage of participants — p=<.001
Phase 4 N=20 Organic Cation Transporter 1 (OCT1), on Response to Metformin in Healthy Subjects
Other Conditions That May Be A Focus of Clinical Attention
Primary: Area Under the Curve (AUC) of Blood Concentration-time of Metformin — 9,200; 7,700 hour * µg/L
Phase 2 N=24 Safety and Effectiveness of a Vaccine for Prostate Cancer That Uses Each Patients' Own Immune Cells.
Prostate Cancer
Primary: Adverse Event — 22; 2; 4; 0 Adverse Events — p=0.001
Phase 4 N=21 The Role of P-glycoprotein in Sitagliptin Clinical Pharmacology
Healthy
Primary: Sitagliptin Monotherapy: Sitagliptin Area Under the Plasma Concentration-time Curve (AUC) From 0 to Infinity — 3638; 3502; 3129 ng*hr/ml — p=0.83
Phase 4 N=35 Efficacy and Safety of SEROQUEL Extended Release (XR) in Acute Schizophrenia
Schizophrenia
Primary: Change From Baseline in Positive and Negative Syndrome Scale Excited Component (PANSS-EC) Score — -7.5 Scores on a scale
Phase 2 N=33 Safety and Efficacy of TACLONEX Ointment in Adolescent Patients (Aged 12 to 17 Years) With Psoriasis Vulgaris
Psoriasis Vulgaris
Primary: Adverse Drug Reactions — 2 participants
Phase 2 N=51 Melphalan, Fludarabine, and Alemtuzumab Followed by Peripheral Stem Cell Transplant in Treating Patients With Hematologic Cancer
Leukemia · Lymphoma · Multiple Myeloma and Plasma Cell Neoplasm
Primary: Overall Survival — 37 participants