6,678 trials
Parkinson Disease
Primary: Change From Baseline in Daily "OFF" Time at Week 18 — -0.8 hours — p=<0.001
Hypertension
Primary: Change in Mean Sitting DBP Between Week 0 (Visit 2) and Week 8 (Visit 3) — -9.3 mmHg — p=<0.001
Constipation Drug Induced
Primary: Occurrence of Bowl Movement — 2; 2; 5 Participants
Osteoporosis, Postmenopausal · Osteoporosis · Osteoporotic Fractures
Primary: Bone Density of the Total Hip — 4.62; -0.19; 3.74; 0.48 Percent change — p=.007
Knee Disease · Arthritis Knee · Pain, Acute
Primary: Post-operative Pain — 4.29; 3.57 visual analog pain scale
Pain, Postoperative · Urethral Stricture
Primary: Participant Pain Control: Numerical Rating Scale (NRS) — 1.2; .625 score on a scale
Hospital-Acquired Pneumonia
Primary: Percentage of Participants With Clinical Cure at Test of Cure (TOC) Visit: Clinical Modified Intent-to-Treat (cMITT) Population — 62.7 Percentage of participants
Human Immunodeficiency Virus
Primary: Tenofovir-diphosphate (TFV-DP) Concentration — 217; 1041; 578; 789 femtomoles
Tobacco Dependence · Withdrawal Symptoms · Smoking Cessation
Primary: The Number of Participants Who Have Continuous Abstinence as Verified by Breath Carbon Monoxide or Urine Cotinine — 17; 9; 9 Participants
Herpes Zoster
Primary: Incidence Rate of Confirmed Herpes Zoster (HZ) Cases — 0.0; 8.2 Cases per 1000 person-years — p=<0.0001
Hepatic Disease
Primary: Accuracy of CEUS at Differentiating Focal Nodular Hyperplasia (FNH) From Hepatocellular Adenoma (HCA) — 66.7; 64.0; 71.9; 90.6 percentage of lesions
Radiocontrast-induced Nephropathy
Primary: Changes in Renal Blood Flow — 9590.8; 5105.4; 8529.4; 5228.4 h.mL/min
Migraine
Primary: Mean Change From Baseline in the Treatment Satisfaction Questionnaire for Medication (TSQM) Overall Satisfaction Scale Score at Week 24 by SoC — 42.33; 34.42 Score on a…
Williams Syndrome · Anxiety
Primary: Mean 16-Week Change in Pediatric Anxiety Rating Scale 5-Item Total Score — -7.9 score on a scale — p=<0.001
Smallpox
Primary: AUC0-t — 29500 ng*h/mL