12,372 trials
Urinary Bladder, Overactive
Primary: Number of Participants With and Severity of Treatment-Emergent Adverse Events (TEAEs) — 72; 10; 20; 8 Participants
Persistent Asthma
Primary: Standardized Baseline-Adjusted Trough Morning Forced Expiratory Volume in One Minute (FEV1) Area Under the Effect Curve From Time Zero to 12 Weeks (AUEC(0-12wk)) by…
Heart Failure · Respiratory Failure
Primary: ICU-Free Days — 20; 19.4 Days
Childhood Embryonal Tumor · Childhood Extracranial Germ Cell Tumor · Childhood Extragonadal Germ Cell Tumor
Primary: Event-Free Survival (EFS) — 87.0 Percent probability
HIV-1 Infection
Primary: Percentage of Participants With HIV-1 RNA < 50 Copies/mL at Week 48 as Defined by the US FDA-Defined Snapshot Algorithm — 93.7; 93.9 percentage of participants — p=1.00
Friedreich's Ataxia
Primary: Change From Baseline to Week 26 in the Friedreich's Ataxia Rating Scale (FARS)-mNeuro Score — -0.6; -1.0 units on a scale — p=0.5442
Arthritis, Rheumatoid
Primary: The Proportion of Patients Meeting the American College of Rheumatology 20% (ACR20) Response Criteria at Week 12 — 67.0; 61.1 Percentage of Patients
Diabetes · Diabetes Mellitus, Type 2
Primary: Change in HbA1c (Glycosylated Haemoglobin) — -1.48; -1.46 Percentage of glycosylated haemoglobin — p=<0.0001
Crohn's Disease
Primary: Percentage of Participants With Mucosal Healing and No Deep Ulcerations — 30.3; 45.9 percentage of participants — p=0.010
Urge Urinary Incontinence · Overactive Bladder
Primary: Change in Urge Urinary Incontinence (UUI) Episodes — -3.13; -3.15; -3.32; -3.25 Mean change in UUI episodes from baselin
Rhinitis, Allergic, Perennial
Primary: Correlations of Experience With Allergic Rhinitis Nasal Sprays Questionnaire (EARNS-Q) Preference Module With Treatment Satisfaction Questionnaire for Medicines (TSQM)…
Osteoporosis
Primary: Percentage Change From Baseline in Lumbar Spine Bone Mineral Density (BMD) at Month 24 — 6.86; 1.27 Percentage change — p=< 0.001
Diabetes · Diabetes Mellitus, Type 2
Primary: Change From Baseline in HbA1c — 7.96; 7.89; 6.63; 6.59 Percentage of glycosylated haemoglobin
Obsessive Compulsive Disorder
Primary: Mean Change From Baseline in the Japanese Children's Yale-Brown Obsessive Compulsive Scale 10-item Total Score at the End of Treatment in the First Phase — -10.5; -6.6…
Myocardial Infarction
Primary: Pharmacology Arm - Major Adverse Ischemic Cardiac Events and Major Bleeding Events — 166; 218 Participants