6,678 trials
Osteoporosis
Primary: Percentage Change in the Bone Formation Marker N-terminal Propeptides of Human Procollagen Type I (P1NP) From Baseline to End of Trial — 446.1; -6.2 percent change…
Femoral Fractures
Primary: Total Blood Loss — 370.7; 426.2 Milliliters (mL) — p=0.348
Hepatitis B
Primary: Number of Subjects With an Anamnestic Response to a Challenge Dose of Hepatitis B Virus (HBV) Vaccine as Measured by Enzyme-Linked Immunosorbent Assay (ELISA). — 8; 13…
Bradycardia
Primary: Performance of Activities of Daily Living Tests (6-minute Walk and Sweep) — 19.28; 18.09; 18.05 repetitions — p=0.004
Other Surgical Procedures
Primary: Number of Participants With Complete Sensory Block — 38; 39; 39 participants — p=1
Hepatitis C
Primary: Virological Response (Intention to Treat) — 19; 21; 7; 2 participants
Bacterial Vaginosis
Primary: Cure of Bacterial Vaginosis — 75; 73; 77 participants
Cardiorenal Syndrome · Chronic Allograft Nephropathy
Primary: CAD (Chronic Allograft Dysfunction) Degree — 1.24; 1.22; 1.43; 1.68 Scores on a Banff scale — p=<0.05
Major Depressive Disorder
Primary: Time to Confirmed Response by ≥ 50% Change From Baseline Reduction in the Hamilton Depression Rating Scale-17 Items (HAMD-17) — 6.4; 8.0 weeks — p=0.213
Hypertension
Primary: Percentage of Participants With Colonic Pathology — 25.5; 25.1 Percentage of participants
Rheumatoid Arthritis
Primary: Percentage of Subjects Without Baseline Protective Titers Achieving a ≥ 2-fold Titer Increase in ≥ 3 of 6 Pneumococcal Antigens (6B, 9V, 14, 18C, 19F, and 23F) at Week…
Post-Menopausal Osteoporosis
Primary: Absolute Change From Baseline in Actual Glomerular Filtration Rate (GFR) (Using Abbreviated Modification of Diet in Renal Disease [MDRD] Formula) — 72.5; 71.5; 70.5…
Type 2 Diabetes Mellitus
Primary: Change in HbA1c (Percent) — -0.38; -0.68 Percent HbA1c — p=.012
Metabolic Syndrome X
Primary: Percentage Change From Baseline in Ratio of Apolipoprotein (ApoB/ApoA1) at Week 6 — -44.40; -36.50 percent change
Essential Hypertension
Primary: Change From Baseline to Week 6 in the Mean 24-hour Ambulatory Diastolic Blood Pressure (MADBP) — -4.10; -5.24 mm Hg