Phase 4 N=89 CONCERTA Lab School Study
Attention Deficit Hyperactivity Disorder
Primary: Hour 4 Permanent Product Math Test Attempted Score (PERMP-Attempted) — 88.0; 116.1 Problems attempted — p=<0.0001
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=659 Randomized Study Comparing the Efficacy and Safety of Varenicline Tartrate to Placebo in Smoking Cessation When Subjects Are Allowed to Set Their Own Quit Date
Smoking Cessation
Primary: Percentage of Participants With 4-week Continuous Abstinence (CA) — 53.9; 19.4 Percentage of participants — p=<0.0001
Phase 4 N=370 A Study Comparing the Efficacy and Safety of Duloxetine and Placebo for the Treatment of Depression in Elderly Patients
Major Depressive Disorder
Primary: Change From Baseline to 13 Weeks in Hamilton Depression Rating Scale (HAMD-17) Maier Subscale — -4.34; -3.90 units on a scale — p=0.397
Phase 4 N=999 A Dose Escalation Study of a Combination Antihypertensive Drug in the Treatment of Various Groups of Patients Who do Not Respond to Single Drug Treatment of Their High Blood Pressure
Hypertension
Primary: The Percentage of Patients Who Achieve Seated Systolic Blood Pressure Goal (<140 mm Hg for Non-diabetics and <130 mm Hg for Diabetics) From Baseline to 12 Weeks — 75.8…
Phase 4 N=39 The Effect of Nebivolol in Hypertensive Patients With Coronary Artery Disease
Hypertension · Coronary Artery Disease
Primary: Peripheral Diastolic Blood Pressure (DBP) — 81.1; 78.2; 78.0; 79.3 mmHg
Phase 4 N=308 F38-27: An Evaluation of 2 Different Bowel Cleansing Preparations in Adult Subjects
Colonoscopy
Primary: Efficacy: Percentage of Patients With Successful Preparations Based on a 4 Point Scale — 77.6; 80.1 percent of participants — p=0.005
Phase 4 N=96 A Study of the Effectiveness and Safety of Two Doses of Risperidone in the Treatment of Children and Adolescents With Autistic Disorder
Autistic Disorder · Autism
Primary: Change in Aberrant Behavior Checklist Irritability (ABC-I) Subscale — -3.5; -7.4; -12.4 units on a scale — p=<0.001
Phase 4 N=30 Study to Evaluate Safety, Efficacy and Tolerability of Clobetasol Propionate for Chronic Hand Dermatitis
Hand Dermatosis
Primary: Proportion of Subjects With at Least 1-grade Improvement From Baseline to Day 15 in Investigator's Static Global Assessment Score (ISGA) Score — 96.7 Percentage of…
Phase 4 N=1,742 PEGASUS CRT Study: Atrial Support Study in Cardiac Resynchronization Therapy
Heart Failure
Primary: Clinical Composite Score — 230; 235; 229; 84 participants — p=0.55
Phase 4 N=108 Pediatric Zylet Safety and Efficacy Study
Chalazion · Hordeolum
Primary: Treatment Emergent Adverse Events — 2; 0; 1; 1 participants
Phase 4 N=608 ALPHA Sitagliptin Add on to Metformin (0431-103)
Diabetes Mellitus
Primary: Change From Baseline in HbA1c at Week 24 — -0.6 Percent — p=<0.001
Phase 4 N=220 Study of Urgent PC Versus Sham Effectiveness in Treatment of Overactive Bladder Symptoms
Overactive Bladder
Primary: The Global Response Assessment (GRA) for Overall Bladder Symptoms to Compare the Proportion of Subjects Reporting "Moderately" or "Markedly Improved" Responses on the…
Phase 4 N=668 Evaluation of the Efficacy and Safety of Rosuvastatin 5 mg Versus Pravastatin 40 mg and Atorvastatin 10 mg in Type IIa and IIb Hypercholesterolaemic Patients
Type IIa and IIb Hypercholesterolaemia
Primary: Change in Low Density Lipoprotein Cholesterol (LDL-C) Level After 8 Weeks — -39.4; -30.3; -37.6 percentage of LDL-C decrease
Phase 4 N=50 Intermittent Use of Aerosolized Ribavirin for Treatment of RSV
Hematological Malignancies
Primary: Occurrences of Pneumonia — 4; 3 Participants
Phase 4 N=207 A Study on the Long-term Efficacy of Nebivolol After Withdrawal of Therapy
Hypertension
Primary: Trough Sitting Diastolic Blood Pressure — 81.3; 81.1; 1.8; 7.7 mm HG