Phase 4 N=29 Field of Effects of Two Commercial Preparations of Botulinum Toxin Type A
Wrinkles in Frontal Area
Primary: Horizontal Action Halo Diameter at 28 Days — 1.28; 1.12 centimeter — p=<0.0001
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=473 Study Comparing Tigecycline Versus Ceftriaxone Sodium Plus Metronidazole in Complicated Intra-abdominal Infection (cIAI)
Appendicitis · Cholecystitis · Diverticulitis
Primary: Number of Clinically Evaluable (CE) Patients With Clinical Response of Cure at the Test-of-Cure (TOC) Visit — 162; 150 participants
Phase 4 N=150 Comparison of Seasonal Allergic Rhinitis Treatment With 2 Antihistamines Used in Combination With Intranasal Corticosteroid
Seasonal Allergic Rhinitis
Primary: Mean Change in Reflective Total Nasal Symptom Score (rTNSS) From Baseline — 4.28; 4.15 Units on a scale
Phase 4 N=500 Bispectral Index-guided Sedation for Flexible Bronchoscopy
Flexible Bronchoscopy
Primary: The Number of Participants With Any Hypoxemia Event During Flexible Bronchoscopy — 97; 88 participants — p=0.05
Phase 4 N=97 Assessment of Inflammatory Biomarkers Expressed in a Sjogren's Population: Effect of a Topical Steroid Intervention
Sjogren's Syndrome
Primary: Change in Levels of Biomarkers After Dosing With Maxidex — -1.244; -0.29; -0.033; -0.33 ddCt (Delta-Delta-Ct)
Phase 4 N=162 Evaluation of Irritation That Potentially Could be Caused by Two Facial Gels Applied to Opposite Sides of the Face
Acne Vulgaris
Primary: Facial Irritation and Cutaneous Effects — 1.5; 5.4; 3.1; 7.8 Scores on a Scale
Phase 4 N=10 Analysis of the Peripheral Blood Mononuclear Cells of Patients With Ankylosing Spondylitis During Infliximab Treatment (Study P04465)(COMPLETED)
Spondylitis, Ankylosing
Primary: Number of Genes Which Were Differentially Expressed — 54675; 890; 701 Number of genes — p=<0.05
Phase 4 N=16 Renal and Hormonal Effects of Pioglitazone
Diabetes · Hypertension
Primary: Effects of Pioglitazone on Renal Hemodynamics — 68.0; 62.4 ml/min/1.73m2
Phase 4 N=120 Visual Function After Implantation of Bilateral AcrySof® Toric Natural Intraocular Lens
Cataract
Primary: Visual Acuity (VA) — 0.7; 0.06; 0.05; 0.05 logMAR
Phase 4 N=40 Prevention of N-methyl-D-aspartate (NMDA) Antagonist-induced Psychosis in Kids
Psychoses, Substance-Induced
Primary: Brief Psychiatric Ratings Scale (BPRS) Positive Symptom Subscale Score — 0.00; 0.00; 1.40; 1.00 Scale of 0-6
Phase 4 N=26 Low Cylinder Toric
Cataracts
Primary: Uncorrected Distance Visual Acuity — 0.09 logMAR
Phase 4 N=121 Comparison of Atomoxetine and Placebo in Children With Attention-Deficit/Hyperactivity Disorder (ADHD) and/or Reading Disorder (RD)
Attention Deficit Hyperactivity Disorder · Reading Disorder
Primary: Stop Signal Reaction Time (SSRT) as Derived From the Stop Signal Reaction Time Paradigm — 299.90; 308.82; 265.61; 260.51 milliseconds (msec) — p=0.504
Phase 4 N=23 Functional Magnetic Resonance Imaging (fMRI) Investigation of Nicotine Withdrawal Symptoms
Smoking
Primary: Percent Mean Change in Blood Oxygen-level Dependent (BOLD) Scores During Rapid Visual Information Processing (RVIP) Task — 0.0; 0.2; 0.7; 0.7 Percentage change in BOLD…
Phase 4 N=310 This Study Contains an Active Drug Treatment Group With Mometasone Furoate Nasal Spray and a Placebo (Dummy) Treatment Group for Seasonal Allergic Rhinitis (SAR). (Study P05073)(COMPLETED)
Seasonal Allergic Rhinitis
Primary: Changes in the Total Nasal Symptom Severity Score (TNSS) at 6 Hours After Dosage Administration on Day 1 — -2.01; -1.86 score on a scale — p=0.625
Phase 4 N=343 Efficacy and Safety Study of Fosamax Plus D in Postmenopausal Women With Osteoporosis (0217A-263)
Osteoporosis Postmenopausal
Primary: Patients With Serum 25 OHD (Serum 25-hydroxyvitamin D) Below the Deficiency Level (Less Than 15 ng/ml) at 16 Weeks of Treatment — 2; 55; 134; 77 participants — p=<0.0001