12,372 trials
Cardiovascular Disease · Inflammation
Primary: Mean Concentrations of Inflammatory Markers (TNF-alpha and IL-6) Following 5 Months of Treatment — 1.4; 1.3; 1.4; 1.5 pg/mL
Stage III Kidney Wilms Tumor · Stage IV Kidney Wilms Tumor
Primary: Event Free Survival Probability — 0.79 Probability
Septic Shock
Primary: Time to Shock Reversal — 44.4; 28.6 hours
Hemophilia A With Inhibitors · Hemophilia B With Inhibitors
Primary: Proportion of Successfully Treated Mild/Moderate Bleeding Episodes — .849; .932 Proportion of Success of BEs
Liver Neoplasms
Primary: Sensitivity: Percentage of True Positive Lesions Among All Malignant Lesions Per Truth Standard — 53.2; 64.5; 41.1; 60.5 Percentage of true positive lesions — p=0.0754
Drug/Agent Toxicity by Tissue/Organ · Leukemia
Primary: Asparaginase-Related Toxicity Rate — 26; 28 percentage of participants — p=.60
Chronic Pancreatitis
Primary: Change in Pain Disability Index — 3; 3 Participants
Caries, Dental
Primary: Total Net D12FS Caries Increment (Total of Non-cavitated Lesions (D1), Cavitated Lesions (D2) and Sound Surfaces (S)) — 2.43; 2.68 weighted increment units/13 months…
Diabetic Foot Infection
Primary: Number of Participants With Clinical Response — 43; 63 Participants
HIV · HIV Infections · Acquired Immunodeficiency Syndrome
Primary: Part 1: Percentage of Participants With Plasma HIV-1 RNA Decreases From Baseline Exceeding 0.5 log10 at Day 10 — 58.3; 60.7; 0 percentage of participants — p=<0.001
Asthma
Primary: Number and Percentage of Patients/Caregivers Who Successfully Administered Benralizumab 30 mg Subcutaneously (SC) by Injection With an APFS at Home — 112; 108; 106…
Asthma
Primary: Change From Baseline in Evening (Post Meridiem [PM]) Forced Expiratory Volume in One Second (FEV1) Using Intent-to-Treat (ITT) Population — 0.019; 0.000; -0.104 Liter…
Depression
Primary: Endpoint Hamilton Depression Rating Scale (HAMD) Scores Adjusted for Age, Sex, Treatment Site, and Baseline HAMD Scores. — 15.1; 15.7; 14.9 units on a scale — p=0.74
COPD Patients
Primary: The Rate of Moderate and Severe COPD Exacerbations Defined as: Worsening of ≥2 Major Symptoms or Worsening of 1 Major Symptom Together With ≥1 Minor Symptom for ≥2…
Acute Ischaemic Stroke · Transient Ischaemic Attack
Primary: Number of Participants With Composite of Stroke/MI/Death — 442; 497 Participants — p=0.0670