Phase 4 N=100 A Multimodal Analgesia Protocol Adapted for Ambulatory Surgery
Opioid Use
Primary: Amount of Pain Experienced — 28; 35 Score on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=530 Trial of Andexanet Alfa in ICrH Patients Receiving an Oral FXa Inhibitor
Acute Intracranial Hemorrhage
Primary: Number of Participants Who Achieved Effective Hemostasis — 150; 121 Participants — p=0.0032
Phase 4 N=49 HepB-CpG Series for Healthcare Workers Who Are Hepatitis B Vaccine Nonresponders
Healthcare Worker, Hepatitis B Vaccine, Nonresponder
Primary: Number of Participants Who Failed to Respond to 5 or More Doses of Hepatitis B Vaccine With Aluminum Adjuvant Who Respond to Hepatitis B Vaccine With CpG Adjuvant Series…
Phase 4 N=71 Creatine Augmentation for Adolescent Females With Treatment-Resistant Major Depressive Disorder
Major Depressive Disorder
Primary: Brain Phosphocreatine (PCr) Concentrations — .1812802; .1796093; .1850427; .1876206 Ratio
Phase 4 N=180 Misoprostol Dosing in BMI Greater Than 30
Pregnancy Related · Obesity · Labor Onset and Length Abnormalities
Primary: Interval Time From Labor Induction Initiation to Delivery (Vaginal or Cesarean) — 18.56; 21.59 hours
Phase 4 N=58 Use of Curcumin to Treat Unfavorable Bleeding Patterns in Contraceptive Implant Users
Bleeding · Implants · Breakthrough Bleeding
Primary: Total Number of Days Without Bleeding or Spotting — 17.5; 16.7 days
Phase 4 N=150 Comparison of Nebulized Ketamine to Intravenous Sub-Dissociative Dose Ketamine for Pain
Pain
Primary: Change in in Pain Score at 30 Minutes — 4.7; 4.5 score on a scale
Phase 4 N=34 Lidocaine For Treatment of Post-operative Pain From Donor Sites Following Burn Injury.
Pain
Primary: Pain Change — -3.8; -4.0 units on a scale — p=<0.05
Phase 4 N=30 Study of Daylight Photodynamic Therapy With Aminolevulinic Acid for Actinic Keratoses
Actinic Keratosis
Primary: Percent Change in the Number of Actinic Keratoses — -75 % change in number of actinic keratoses
Phase 4 N=30 Envarsus Neurotoxicity Burden in Liver Transplant Patients
Neurotoxicity · Liver Transplant; Complications
Primary: Change in Neurotoxicity Burden — -5; -4 score on a scale
Phase 4 N=119 Pectoralis Block vs Paravertebral Nerve Blocks for Breast Surgery
Breast Surgery
Primary: Recovery Room Numeric Rating Scale Pain Scores — 3.3; 1.3 score on a scale
Phase 4 N=333 Immunogenicity of H. Influenzae Type b PRP-OMP Vaccines in American Indian and Alaska Native Children (the HibVax Study)
Haemophilus Influenzae Type B Infection
Primary: Anti-PRP IgG Geometric Mean Concentration (GMC) — 0.40; 0.41 μg/mL — p=0.85
Phase 4 N=19 Methylene Blue vs Cyanokit for Intraoperative Vasoplegic Syndrome in Liver Transplant Patients
Vasoplegic Syndrome · Liver Transplant; Complications
Primary: Systemic Vascular Resistance (SVR) — 480; 410; 588; 420 dyne*sec/cm^5
Phase 4 N=565 A Study of VI-0521 on Ambulatory Blood Pressure (ABPM) in Overweight or Obese Subjects
Blood Pressure
Primary: Change From Baseline to Week 8 in Mean Systolic Blood Pressure as Measured by 24-hr ABPM — -3.3; 1.4; -0.1 mmHg — p=< 0.001
Phase 4 N=94 Does PAI Reduce Pain After TKA Among Knee Arthroplasty Patients Receiving ACB & IPACK?
Total Knee Athroplasty
Primary: Pain Scores (NRS, 0-10) With Ambulation on POD1 — 4.55; 4.26 units on a scale — p=0.11