17,261 trials
AIDS Dementia Complex · HIV-1-Associated Cognitive Motor Complex · Human Immunodeficiency Virus
Primary: Change From Baseline to Week 24 in Global Neuropsychological Performance — .24 units on a scale — p=0.0079
Recurrent Platinum Resistant Ovarian Cancer
Primary: Mean Objective Response Rate (ORR) by Independent Central Review (ICR) Using Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST 1.1) — 15.3 percentage of…
Constipation
Primary: Percentage of Participants With a Spontaneous Bowel Movement (SBM) Within 1, 2, 3, 4, and 6 Hours of Treatment — 0; 0; 0; 7 Participants
Halitosis · Tongue Diseases
Primary: Halitosis Measured by Organoleptic Test — 3.2; 3.2; 2.9; 1.4 score on a scale
Muscle Wasting (Atrophy) After Hip Fracture Surgery
Primary: Change From Baseline in Total Lean Body Mass Measured by DXA (Dual-energy X-ray Absorptiometry) at Weeks 12 and 24 — 1.066; 1.052; 1.059; 1.009 kg — p=<.0001
Heart Failure
Primary: Percentage of Participants With Clinically Relevant Hypotension up to 6 Hours After the End of Study Drug Infusion — 8.3; 20.4; 18.3; 21.1 Percentage of participants
Hepatocellular Carcinoma · Metastasis · Invasion
Primary: Overall Survival — 333; 290 days — p=0.4593
CIDP · Chronic Inflammatory Demyelinating Polyneuropathy
Primary: Muscle Strength
Sickle Cell Disease
Primary: Pain Rating Using Visual Analog Scale at Day 1 and Day 5 — 40.5; 45.8; 30.3; 38.5 score on a scale
Alcohol Dependence · Cocaine Dependence
Primary: Visual Analog Scale Alcohol Craving — 20; 35 units on a scale — p=.02
Epilepsy
Primary: AUC 0-t — 7290.40; 5682.09; 8288.63 hr*ng/mL
Castration Resistant Prostate Cancer
Primary: Number of Patients With PSA Response From Dose Escalation — 0 Participants
Familial Partial Lipodystrophy · Hypertriglyceridemia · Fatty Liver
Primary: Change in Fasting Serum Triglyceride (at 12 Weeks) — -0.44; -20.27 percent change — p=0.517
Nicotine Dependence · Smoking
Primary: Number of Participants With Biochemically-verified Abstinence From Smoking on Days 1-3 of the Protocol. — 8; 6 Participants
Parkinson Disease
Primary: Change in the MDS-UPDRS Tremor Subscore — 0.25; 0.27 score on a scale — p=0.5