N/A N=40 Jackson Pediatric Acupressure for Opioid Tapering
Iatrogenic Withdrawal Syndrome
Primary: Easing of Withdrawal Symptoms as Measured by the Withdrawal Assessment Tool (WAT-1) — 3.0; 3.0 Score on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=19 Blood Pressure, Cerebral Blood Flow and Cognition in Spinal Cord Injury
Spinal Cord Injury
Primary: Systolic Blood Pressure — 116.3; 98.0 mmHg
N/A N=22 Safety and Feasibility of the Use of the Dual Robotic Arm Accessory With the Levita Magnetic Surgical System in Laparoscopic Procedures
Bariatric Surgery Candidate · Cholelithiases · Other Disease
Primary: Adverse Events- Safety — 0 Device related adverse events
N/A N=529 Advancing Understanding of Transportation Options
Diabetic Retinopathy · Macular Degeneration · Glaucoma
Primary: Decisional Conflict Scale (DCS) Scores at Day 0 (Post-intervention) — 15.2; 12.3 units on a scale
Phase 4 N=21 Ketone Monitoring in T1D: Effect of SGLT2i During Usual Care and With Insulin Deficiency
Diabetes Mellitus, Type 1
Primary: Capillary Blood Beta-hydroxybutyrate (BOHB) During Outpatient Care — 0.1; 0.2 mmol/L — p=< 0.0001
Phase 2 N=423 Efficacy and Safety of MEDI6570 in Patients With a History of Myocardial Infarction
Coronary Heart Disease (CHD)
Primary: Change From Baseline to Day 253 in Non-calcified Plaque Volume in the Most Diseased Coronary Segment (NCPVMD), as Measured by Computed Tomography Angiography (CTA)…
Phase 3 N=168 A Study of the Efficacy and Safety of Frespaciguat (MK-5475) in Participants With Pulmonary Arterial Hypertension (INSIGNIA-PAH: Phase 2/3 Study of an Inhaled sGC Stimulator in PAH) (MK-5475-007)
Pulmonary Arterial Hypertension · Hypertension, Pulmonary
Primary: Phase 2 Cohort: Mean Percent Change From Baseline in Pulmonary Vascular Resistance (PVR) at 12 Weeks — 4.3; -4.9; -17.6; -15.6 Percentage Change — p=0.068
N/A N=20 Trial to Compare the SherpaPak™ Device vs Cold Storage
Organ Transplant
Primary: Absence of Moderate to Severe Primary Graft Dysfunction (Left or Right Ventricle) — 10; 10 Participants
Phase 4 N=61 Oral Caffeine Use for Pain Management in AIS Patients After Spinal Fusion
Adolescent Idiopathic Scoliosis
Primary: Total Post Operative Oral Morphine Milligram Equivalents (MME)/Kilogram (Kg) for Hospital Stay — 0.83; 0.92 MME/Kg
N/A N=224 FUnctional diagnoSIs of corONary Stenosis (FUSION)
Coronary Artery Disease · Coronary Stenosis
Primary: Sensitivity and Specificity of Virtual Flow Reserve (VFR) Against Fractional Flow Reserve (FFR) — 82; 136 vessels
Phase 4 N=34 Effect of Coconut Water on Hydration Status in Pediatric Population
Sports Nutrition
Primary: To Determine the Effect of AC vs EO on Hydration Status in Adolescents Who Perform Physical Exercise of Aerobic Competition. — 53; 36; 15; 32 Number participants…
N/A N=321 Subthreshold Opioid Use Disorder Prevention (STOP) Trial
Opioid-use Disorder
Primary: Days of Risky Opioid Use in Past 180 Days — 12.2; 15.5 days
Phase 2 N=9 AZD4573 in Novel Combinations With Anti-cancer Agents in Patients With Advanced Blood Cancer
Advanced Haematological Malignancies
Primary: Module 1: Number of Participants With Adverse Events — 9; 28; 4; 16 Participants
N/A N=756 Project to Improve Communication About Serious Illness--Hospital Study: Comparative Effectiveness Trial (Trial 2)
Dementia · Chronic Disease · Neoplasm Metastasis
Primary: EHR Documentation of Goals of Care Discussions — 0.271; 0.317; 0.206 Proportion of participants — p=0.023
Phase 1 N=16 A Study in Healthy Men to Test How Itraconazole Influences the Amount of BI 1358894 in the Blood
Healthy
Primary: Area Under the Concentration-time Curve of BI 1358894 in Plasma Over the Time Interval From 0 Extrapolated to Infinity — 1623.89; 3128.75 Nanomoles*Hour per Liter