Phase 4 N=136 Rocklatan® Evaluation
Glaucoma
Primary: Mean Percent Change From Baseline in Intraocular Pressure (IOP) at Week 12 — -21.2; -15.7; -16.9; -18.5 percent change
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=20 Awake Caudal Catheter vs General Anesthesia
Inguinal Hernia
Primary: Number of Participants With Return to Baseline Respiratory Function. — 11; 9 Participants
Phase 4 N=201 Adenosine Contrast CorrELations in Evaluating RevAscularizaTION
Percutaneous Coronary Intervention
Primary: Comparison Between Contrast Fractional Flow Reserves (cFFR) and Adenosine Fractional Flow Reserves (aFFR) — 0.8922 proportion of lesions with agreement
Phase 4 N=110 Comparing the Effects of Different Doses of Dexamethasone to Treat Inpatient COVID-19
Covid19
Primary: Number of Participants With Clinical Improvement of Greater Than or Equal to 2 Points Using the WHO-OSCI at Day 28 — 37; 43 Participants
Phase 4 N=41 Safety and Efficacy of Chronic Hypnotic Use 2
Chronic Insomnia
Primary: Total Number of Capsules Taken During Discontinuation From Either Active Drug vs Placebo Over a Two Week Period — 0.43; 2.6; 6.3 Total number capsules chosen — p==0.05
Phase 4 N=194 The Aim of This Study is to Investigate the Persistence of Antibody Response in Adults up to 15 Years After One Booster Dose of GlaxoSmithKline (GSK) Biologicals' Encepur Adults Vaccine
Virus Diseases
Primary: Percentage of Participants With Detectable TBE Neutralizing Antibody Titers Equal to or Above 10 at Year 11 — 100; 100; 99.0 Percentage of participants
Phase 4 N=62 Antidepressant Controlled Trial for Negative Symptoms in Schizophrenia
Schizophrenia
Primary: PANSS Negative Symptom Score — 21.5; 23 units on a scale — p=0.36
Phase 4 N=65 Preemptive Analgesia With Celecoxib for Acute Dental Pain Management
Pain, Postoperative
Primary: Pain as Assessed by a Visual Analogue Scale (VAS) — 4; 2.33 score on a scale
Phase 4 N=500 A Study to Evaluate Immunogenicity and Safety of GlaxoSmithKline (GSK)'s Infanrix Hexa Vaccine (DTPa-HBV-IPV/Hib) Versus MCM Vaccine BV's Vaxelis Vaccine (DTaP5-HBV-IPV-Hib) in Healthy Infants and Toddlers
Diphtheria
Primary: Anti-polyribosylribitol Phosphate (Anti-PRP) Antibody Concentrations at Month 11, Based on Per Protocol Set (PPS) — 11.61; 12.66 μg/mL
Phase 4 N=14 Using Triamcinolone Acetonide to Reduce Pain After Scleral Buckle Surgery
Retinal Detachment
Primary: Post Operative Pain Day 1 — 2.2; 1.0 score on a scale
Phase 4 N=66 Vaccination for Recovered Inpatients With COVID-19 (VATICO)
Covid19
Primary: Ratio of 48-Week to Baseline Neutralizing Antibody (NAb) Levels — 0.3722; 0.5883; 0.2088; 0.3073 ratio of geometric mean responses
Phase 4 N=246 Enhancing Preventive Therapy of Malaria In Children With Sickle Cell Anemia in East Africa (EPiTOMISE)
Malaria,Falciparum
Primary: Incidence of Clinical Malaria Per Patient Year — 0.04; 3.05; 1.36 episodes/patient year
Phase 4 N=55 Benefit of Placebo and Different Concentrations of Triamcinolone Acetonide in Nail Psoriasis
Nail Psoriasis · Nail Diseases
Primary: Lowest Effective Concentration of Intralesional Triamcinolone Acetonide for Nail Psoriasis — 2.5 mg/mL
Phase 4 N=80 Intrathecal Opioids for Colorectal Resection
Colorectal Surgery · Pain, Postoperative · Analgesic, Opioid
Primary: Postoperative Pain Control — 4.5; 1.6; 1.75; 2.75 score on a scale
Phase 4 N=19 Treatment of Keloids With Fractional Erbium Laser-Assisted 5-Fluorouracil Versus Laser-Assisted Corticosteroid
Keloid Scar
Primary: Change in Patient and Observer Scar Assessment Scale (POSAS) Score From Baseline to Final Visit — -20; -20.6 score on a scale