12,372 trials
Major Depressive Disorder (MDD)
Primary: Change in Total MADRS Scores From Baseline to Week 8 — -24.95; -18.95; -23.89 units on a scale
Adenocarcinoma of the Colon · Stage III Colon Cancer
Primary: Disease-free Survival (Arms A and D: Wild-type KRAS Patients) — 74.6; 71.5 percentage of participants
Metabolism and Nutrition Disorder · Obesity
Primary: Change From Baseline in Fasting Body Weight — -7.98; -2.62 percent change — p=<0.0001
Pain
Primary: The Number of Participants With Adverse Events as a Measure of Safety. — 5; 22; 13; 60 participants
Dental Plaque · Gingivitis
Primary: Dental Plaque Scores — 3.33; 3.19; 3.31 units on a scale — p=0.434
Allergy
Primary: Scores on a Scale [Net Average Combined Daily Rhinoconjunctivitis Symptom (RSS) and Medication Scores] — 0.853; 1.687 Scores on a scale — p=<0.05
Heart Valve Diseases
Primary: Atrial Fibrillation Incidence After Open Cardiac Valve Repair — 6; 13 participants
Atrial Fibrillation
Primary: Number of Participants With Composite of the Following Events, Adjudicated Centrally: Stroke, Transient Ischemic Attack, Non-central Nervous System Systemic Embolism…
Pregnancy · Unexplained Infertility
Primary: Multiple Gestation Rate Following Recruitment of Multiple Follicular Development With an AI, as Compared to CC and FSH. — 9; 8; 34 number of multiples
Familial Hypercholesterolaemia
Primary: Percent Change From Baseline in LDL-C — -37.86; -43.67; -42.88 Percentage change — p=<0.001
Acromegaly
Primary: Percentage of Participants With a Reduction of Mean GH Level to <2.5 μg/L and the Normalization of IGF-1 — 31.3; 19.2; 39.4; 21.8 Percentage of Participants — p=0.007
Rheumatoid Arthritis
Primary: 12 Month Change in 7-Joint Ultrasound (US) Inflammatory Score — 11.4 units on a scale — p=<0.01
RDS of Prematurity
Primary: Duration of NIV Support — 89; 87 HOURS — p=< 0.05
Diabetes Mellitus, Type 2
Primary: Glycosylated Hemoglobin (HbA1c) Change From Baseline — -1.10; -0.87; -0.39 percentage of HbA1c — p=<0.001
Infertility
Primary: Number of Oocytes Retrieved — 4; 3.4 oocytes