Early Phase 1 N=22 Effects of Drugs on Responses to Brain and Emotional Processes
Autism Spectrum Disorder · Healthy
Primary: Change in Responses to Affective Touch — 3.01; 4.06 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=5 Impact of Custom Assistive and Adaptive Technology in Rehabilitation
Disability Physical · Brain Injuries · Stroke
Primary: The PIADS (Psychosocial Impact of Assistive Devices) Mean Score — 2.58; 2.07; 2.05; 6.8 score on a scale
N/A N=10 VisionRT-based Deep Inspiration Breath-hold (DIBH) Respiratory Motion Management Strategy, A Pilot Study for Thoracic and Abdominal Tumors
Thoracic Cancer · Abdominal Cancer
Primary: Correlation Between Kilovoltages X-ray Images of the Diaphragm and the Surface Guided Motion Analyzed With Matlab — 0.01; 0.07 correlation coefficient
N/A N=120 Digital Health Interventions for Obsessive Compulsive Disorder (OCD)
Obsessive-Compulsive Disorder
Primary: Difference in OCD Symptom Severity at the End of Week 12 — 25.12; 23.77; 18.68; 20.49 score on a scale — p=0.0871
N/A N=10 Pilot Study: Can Ultrasound Guided Biopsy be Used as an Alternative to Hysteroscopy?
Endometrial Cancer · Endometrial Neoplasms · Endometrial Hyperplasia
Primary: Number of Participants Whose Sample Was Successfully Analysed by Histological Diagnosis — 9 Participants
N/A N=60 Histerectomy Vs Partial Myometrial Resection for Placenta Accreta Spectrum
Placenta Accreta
Primary: Feasibility: Proportion of Eligible Patients Who Agree to Participate in the Study. — 60 Participants
Phase 1 N=15 Phase 1/1b Study With Nab-sirolimus for Patients With Severe Pulmonary Arterial Hypertension
Pulmonary Hypertension
Primary: Dose-limiting Toxicities — 0; 0; 0; 0 Participants
N/A N=448 Safety and Suitability of ICL for Correction of Refractive Errors Without the Use of Dispersive OVDs
Refractive Errors · Myopia · Myopic Astigmatism
Primary: Unaided Visual Acuity After the Procedure — 0.264; 0.227 LogMar vision
N/A N=50 Effects of Blood Flow Restriction Rehabilitation After Anterior Cruciate Ligament Reconstruction
ACL Tear
Primary: Determine if BFR Changes Loss of LE Lean Muscle Mass — 8.97; 8.97; 8.37; 8.93 kg
N/A N=50 A Study of Acute Kidney Injury in Care Transitions
Acute Kidney Injury
Primary: Number of Subjects to Complete the ACT Program — 22 Participants
Phase 2 N=16 Safety, Immunogenicity and Efficacy of the Blood-stage Plasmodium Vivax Malaria Vaccine Candidate PvDBPII in Matrix M1
Malaria, Vivax
Primary: Safety of the PvDBPII-Matrix M1 Vaccine Candidate, Assessed Through Collection of Data on the Frequency, Duration and Severity of Solicited and Unsolicited Adverse…
Phase 2 N=88 A Study of Seltorexant in Participants With Probable Alzheimer's Disease
Alzheimer Disease
Primary: Change From Baseline in Neuropsychiatric Inventory Clinician Version (NPI-C) Sum of Agitation and Aggression Domain Scores (NPI-C A+A) at Day 43: Analyzed Under Estimand…
Phase 3 N=16 A Study of TAK-771 in Japanese People With Primary Immunodeficiency Diseases (PID)
Primary Immunodeficiency Diseases (PID)
Primary: Epoch 2: Serum Trough Levels of Total IgG Antibodies After Administration of TAK-771 — 9.372; 8.741; 8.929; 9.150 grams/Liter (g/L)
Phase 2 N=1,380 Safety and Immunogenicity of RNA-based Vaccines Against SARS-CoV-2 Variants in Healthy Participants
SARS-CoV-2 Infection · COVID-19 · SARS-CoV-2 Acute Respiratory Disease
Primary: All Parts - Percentage of Participants Reporting Local Reactions at the Injection Site (Pain, Tenderness, Erythema/Redness, Induration/Swelling) — 19; 20; 17; 19…
N/A N=99 Study to Evaluate Patient Reported Outcome (PRO) and Physical Activity in Japanese Patients With HR+/HER2- Advanced Breast Cancer Treated With Palbociclib Plus Endocrine Therapy or Endocrine Monotherapy
Breast Cancer
Primary: Change From Baseline in European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-30 (Items) [EORTC-QLQ-C30] Global Health Status (GHS)…