17,261 trials
Acute, Perforated Appendicitis
Primary: Number of Participants With Postoperative Intra-abdominal Abscess — 6; 8 Participants
Smoking Cessation
Primary: Percentage of Participants With Abstinence for the Last 4 Weeks of Treatment From Weeks 9-12 — 15.31; 8.72; 5.64 percentage of participants — p=0.0027
Schizophrenia
Primary: QTcB Change — 416.50; 416.41; 418.39; 423.27 ms
Postoperative Nausea and Vomiting
Primary: Number of Participants With Complete Response (CR), No PONV Symptoms, Nausea — 8; 25; 24; 28 Participants
Metabolic Syndrome · Hypertension
Primary: Change in Insulin Stimulated Glucose Disposal Over 12 Week Study Period — 0.76 mg/kg lean body mass/minute — p=0.2068
Bladder Cancer
Primary: Pathologic Complete Response Rate of Sunitinib — 0 Participants
Venous Thromboembolism
Primary: Median Dose of Dalteparin Required to Achieve Prespecified Therapeutic Anti- Factor Xa Level — 125 IU/mL
Glioblastoma Multiforme
Primary: Percentage of Subjects With Progression-free Survival — 7.5; 15.0 percentage of subjects
Adenocarcinoma · Colorectal Cancer · Ovarian Cancer
Primary: Number of Participants With Complete Responses (CRs), Partial Responses (PRs,) Stable Disease and Progressive Disease in the Ovarian Cancer and Breast Cancer Cohorts…
Major Depressive Disorder · Depression
Primary: Montgomery-Asberg Depression Rating Scale Comparison to Baseline — 29.50; 15.83 units on a scale
Low-Grade Lymphoma
Primary: Number of Participants With Objective Response — 1; 2; 14; 6 Participants
Tumors With CDK4/6 Pathway Activation
Primary: Number of Participants With Solid Tumor Response ≥ 16 Weeks for Based Upon Local Investigator Assessments — 0; 3; 16; 71 Participants
Follicular Lymphoma · B-cell Lymphoma · Non-Hodgkin's Lymphoma
Primary: Overall Response Rate (ORR): Proportion of Subjects Achieving the Best Overall Responses of Complete Response (CR) or Partial Response (PR) — 51; 15 Participants
Diarrhea · Gastrointestinal Complications · Unspecified Childhood Solid Tumor, Protocol Specific
Primary: Number of Participants With Treatment-free Remission at 1 Year After Study Completion — 2 Participants
Mild Cognitive Impairment
Primary: Change in Baseline Standard Uptake Ratio Values (SUVr) of Florbetapir PET at 3 Months — -3.83 standard uptake value ratio