12,372 trials
High Risk Stage III Melanoma
Primary: Recurrence Free Survival (RFS) Per Independent Review Committee (IRC) in the Intent to Treat (ITT) Population — 26.09; 17.05 months — p=0.0013
Alpha 1-Antitrypsin Deficiency
Primary: Treatment-emergent Adverse Events (TEAEs) Defined as Any Adverse Event (AE) Occurring During or After the Start of the First Study Drug Infusion. — 38; 26; 17; 5…
Migraine
Primary: Percentage of Participants With At Least One Triptan-Related Adverse Experience (AE) — 5.0; 11.2 Percentage of Participants — p=<0.001
Neoplasms, Breast
Primary: Number of Participants (Par.) With Any Recurrence of the Initial Disease, Second Primary Cancer, Contralateral Breast Cancer, or Death (Disease-free Survival [DFS])…
Attention Deficit Hyperactivity Disorder
Primary: Change From Baseline in the Attention-Deficit/Hyperactivity Disorder Rating Scale-IV-Parent Version:Investigator-Administered and Scored (ADHD-RS-IV-PV:IR) Total Score…
Deep Venous Thrombosis
Primary: Incidence of Post-thrombotic Syndrome (PTS) — 44; 37 participants — p=.58
Chronic Hepatitis C Genotype 1
Primary: Percentage of Participants Achieving Sustained Virologic Response At Follow-up Week 24 (SVR24) Among Participants Who Received At Least One Dose of Any Trial Medication…
Gastroesophageal Reflux Disease
Primary: Daytime Heartburn, Number of Days in Week Symptoms Intensity Score < 3 (Better) — 6.6; 5.9; 6.1 days — p=0.04
Neoplasms, Breast
Primary: Disease-Free Survival (DFS) at the Primary Analysis — 1.9; 1.3; 1.0; 1.5 Years — p=0.048
Onychomycosis of Toenails
Primary: Complete Cure (Completely Clear Nail and Negative Mycology) of Target Great Toenail at Week 52 — 36; 3; 360; 202 participants — p=<0.001
Coronary Computed Tomographic Angiography
Primary: Contrast to Noise Ratio — 18.6; 20.5 CNR
Onychomycosis of Toenails
Primary: Complete Cure (Completely Clear Nail and Negative Mycology) of Target Great Toenail at Week 52 — 26; 1; 373; 193 participants — p=0.001
Infertility
Primary: Total Number of Oocytes Retrieved — 11.6; 9.7 number of oocytes — p=0.012
Pulmonary Disease, Chronic Obstructive
Primary: Change From Baseline (BL) in 0 to 24 Hour Weighted Mean Forced Expiratory Volume Over 1 Second (FEV1) at Day 84 — 0.213; 0.112 Liters — p=<0.001
Postoperative Nausea and Vomiting
Primary: Proportion of Patients With no Emetic Episodes in the Overall Time Period 0-72 Hours Post-operatively — 88.0; 84.0 percentage of patients