N/A N=69 Evaluating the Effect of SOLIUS UV Light Source in Improving Vitamin D Status
Vitamin D Deficiency · Vitamin D Insufficiency
Primary: Change in Serum 25-Hydroxyvitamin D [25(OH)D] — 10.14; -2.3 ng/mL
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 1 N=79 Safety, Pharmacokinetics,and Antiviral Activity of RV299 Against Respiratory Syncytical Virus (RSV)
Respiratory Syncytial Virus (RSV)
Primary: Area Under the Curve (AUC) for RSV-A Memphis 37b Viral Load Determined by Quantitative Real Time Reverse Transcription Polymerase Chain Reaction (qRT-PCR) — 350.99…
Phase 3 N=543 Study of Sacituzumab Govitecan-hziy Versus Treatment of Physician's Choice in Participants With HR+/HER2- Metastatic Breast Cancer
Metastatic Breast Cancer
Primary: Progression-Free Survival (PFS) by Blinded Independent Central Review (BICR) Assessment — 5.5; 4.0 months — p=0.0001
N/A N=95 Vitamin D to Improve Outcomes by Leveraging Early Treatment: Long-term Brain Outcomes in Vitamin D Deficient Patients
Cognitive Decline
Primary: 12-month Cognition as Measured by the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) — 79.6; 82.1 units on a scale
N/A N=16 Thermal-Imaging Comparison of Nerve Blocks for Bilateral Mastectomy
Anesthesia, Conduction
Primary: Skin Temperature Increase From Baseline — 1.9; 2.3 degrees C
Phase 1 N=12 TMI With HD Mel in ASCT for R/R Multiple Myeloma (BMT-03)
Multiple Myeloma, Relapsed · Multiple Myeloma, Refractory to Standard Treatment
Primary: Maximum Tolerated Dose (MTD) of Gy — NA Participants
Phase 2 N=16 ZW25 in Women With Endometrial Cancers
Endometrial Cancer · Carcinosarcoma
Primary: Overall Response Rate/ORR of Participants — 1; 15 Participants
N/A N=76 New Visual Acuity and Crowding Tests for Better Detection of Amblyopia
Amblyopia
Primary: Visual Acuity (LogMAR) — 0.004; 0.551; 0.320; 0.005 logMAR
Phase 3 N=106 Efficacy And Safety Evaluation of Glepaglutide in Treatment of Short Bowel Syndrome (SBS)
Short Bowel Syndrome
Primary: Change in Weekly Parenteral Support (PS) Volume — -5.13; -3.76; -2.85 L/week — p=0.0039
N/A N=81 Myofunctional Training for Obstructive Sleep Apnea Patients After Transoral Robotic Surgery
Sleep Apnea, Obstructive
Primary: Apnea Hypopnea Index (AHI) — 44.89; 44.65; 36.87 events per hour — p=<0.05
Phase 3 N=132 Assess Aesthetic Improvement and Onset of QM1114-DP in Subjects With Moderate to Severe Glabellar Lines
Glabellar Frown Lines
Primary: Number of Responders Using the Global Aesthetic Improvement Scale (GAIS) at Month 1 — 92; 3 Participants — p=<0.001
N/A N=65 Exercise in Burn Survivors: Cooling Modalities
Burn Injury
Primary: Change in Core Temperature (°C) During Control Intervention — .578; .920; .622; .885 °C
N/A N=1,001 CONFIDENCE Registry to Assess Safety and Performance of Portico System to Treat Patients With Severe Aortic Stenosis.
Symptomatic Degenerative Aortic Stenosis · Severe Aortic Stenosis
Primary: Cardiovascular Mortality — 15; 6 Participants
N/A N=16 HidraWear Study for Hidradenitis Suppurativa Wounds
Hidradenitis Suppurativa · Hidradenitis
Primary: Ease of Use Day 21 vs Day 0 — 6.47; 0.6 score on a scale
Phase 4 N=277 Effectiveness and Safety of Combination of Amlodipine and Zofenopril in Hypertensive Patients Versus Each Monotherapy
Hypertension
Primary: Change in Mean Sitting Diastolic Blood Pressure (DBP) Between Visit 2 (Week 0) and Visit 4 (Week 8) — -13.5 mmHg — p=< 0.001