12,372 trials
Open-Angle Glaucoma · Ocular Hypertension
Primary: Mean Diurnal IOP Change From Baseline at Month 3 — -8.5; -8.3 millimeters of mercury (mmHg)
Contraception
Primary: Overall Satisfaction Rate at 18 Months (Last Observation Carried Forward, LOCF) — 82.1; 81.9 Percentage of participants
Rheumatoid Arthritis
Primary: Proportion of Patients With ACR20 at Week 24, Comparison Between Fostamatinib and Placebo. — 49.0; 44.4; 34.2 Percentage of responders — p=<0.001
Cystic Fibrosis · Exocrine Pancreatic Insufficiency
Primary: Percent Coefficient of Fat Absorption (CFA%) — 88.28; 62.76 percent CFA — p=<0.001
Cystic Fibrosis · Exocrine Pancreatic Insufficiency
Primary: Percentage of Participants Who Were Responders After 1 Week of Treatment With Study Medication — 68.4 percentage of participants
Chemotherapy Induced Nausea and Vomiting
Primary: Percentage of Participants With a Complete Response in the Delayed Phase of Cycle 1 — 50.7; 26.0 Percentage of participants — p=<0.01
Non-Hodgkin's Lymphoma · Mantle Cell Lymphoma
Primary: Mean Change From Baseline in QT Interval as Corrected by the Fridericia Method (QTcF) at End of Infusion — 410.4; 6.7 milliseconds (ms)
Diphtheria · Polio · Pertussis
Primary: Percentage of Participants With Pre-booster Antibody Persistence and Booster Response to DTaP-IPV-Hep B-PRP~T After Primary Vaccination With Either DTaP-IPV-Hep B-PRP~T…
Pediculosis
Primary: Participants With a Change in Cholinesterase Level at 1 Hour (Day 0). — -1.8; -0.5 percentage change in cholinesterase
Non Small Cell Lung Cancer
Primary: Progression Free Survival (PFS) — 8.38; 9.63 months — p=0.217
Asthma · Lung Diseases
Primary: Pulmonary Function as Measured by Normalized FEV1 Over a 4-6 Year Period — 0.6; -0.5; -0.1 percentage of predicted value
Allergic Rhinitis · Seasonal Allergic Rhinitis
Primary: Mean Change From Baseline in Reflective Total Ocular Symptom Score (rTOSS) — -0.91; -0.63 Score on a scale — p=0.0024
Influenza
Primary: Number of Seroconverted Subjects for Anti- Haemagglutination Inhibition (HI) Antibodies Against Each of the Four Vaccine Influenza Strains of Quadrivalent Influenza…
Relapsing Remitting Multiple Sclerosis
Primary: ARR - PDEs — 0.12; 0.16; 0.11 relapses per year
Primary Dysmenorrhea
Primary: Dysmenorrheal Pain Severity — 3.88; 6.31 units on a scale