Phase 4 N=17 Itraconazole Oral Absorption
Fungal Infection
Primary: AUC — 1624.8; 1365.5; 1282.2; 1848.7 ng*hr/mL
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=353 A Study to Evaluate the Efficacy and Safety of Fremanezumab for Preventive Treatment of Migraine in Patients With Major Depressive Disorder
Migraine · Major Depressive Disorder
Primary: Change From Baseline in Monthly Average Number of Migraine Days During the 12-Week DB Treatment Phase After the First Dose of Study Drug — -2.9; -5.1 days — p=<0.0001
Phase 4 N=95 Stress and Inflammation in Late-Life Depression
Depression · Inflammation
Primary: IL-6 Levels — 5.25; 18.24; 3.69; 6.84 pg/mL — p=.44
Phase 4 N=20 Hydrocodone Compared to Acetaminophen and Ibuprofen for Post-nail Procedure Analgesia
Nail Diseases · Nail Abnormality
Primary: Change From Baseline in Pain Scores on Postoperative Day 2, as Measured by the Wong-Baker 0-to-10 Pain Scale — 2.1; 2.4 score on a scale — p=0.69
Phase 4 N=26 A Study to Compare US Marketed Creon Manufactured With a Modernized Process at an Alternate Manufacturing Site and Manufactured With the Approved Manufacturing Process at an Alternate Active Pharmaceutical Ingredient Site, in Participants With Exocrine Pancreatic Insufficiency Due to Cystic Fibrosis
Cystic Fibrosis
Primary: Part 1 Coefficient of Fat Absorption (CFA) — 85.53; 84.59 percentage of fat intake absorbed
Phase 4 N=63 Maintain Respiratory Muscle Function and Reduce Pneumonia Risk in Cancer Patients
Cancer
Primary: Sniff Nasal Inspiratory Pressure (SNIP) — 90; 87; 89; 109 cmH20
Phase 4 N=32 Magnetic Resonance Imaging of the Effect of Music Listening on Brain Activity Under Anesthesia
Healthy
Primary: Blood Oxygen Level Dependent (BOLD) Response to Sensory Stimuli During Sedation — 0.04; 0.01 arbitrary units — p=<0.001
Phase 4 N=284 Penicillin Allergy Testing in STD Clinics
Penicillin Allergy
Primary: Number of Respondents Who Responded YES to Any Question Defining High Risk Penicillin Allergy Using Questionnaire Developed by the Study — 36; 36 Participants
Phase 4 N=40 Assessing Dextenza Insert After SMILE Procedure
Post Procedural Infection
Primary: Mean Change in Pain — 0.15; 0.20; 0.95; 0.90 Score on a scale from 0-10
Phase 4 N=16 The Effect of Insulin Glulisine Compared With Insulin Aspart on Breakfast Post Prandial Glucose Levels in Prepubertal Children
Type 1 Diabetes Mellitus
Primary: Difference in the Two Hour and Four Hour Post Prandial Blood Glucose Levels Following Administration of Insulin Glulisine Versus Insulin Aspart at the End of the Twenty…
Phase 4 N=20 Afrezza® Dosing Optimization Study
Diabetes Mellitus, Type 1 · Diabetes Mellitus, Type 2
Primary: Post-prandial Glucose Excursion — 6.8; 5.6; 25.9; 21.9 mg/dL
Phase 4 N=32 Narcotic Free TIVA and Incidence of Unacceptable Movements Under Anesthesia During ACDF Surgery
Anterior Cervical Discectomy and Fusion (ACDF)
Primary: Incidence of Unacceptable Movement Under General Anesthesia — 1; 1 Participants
Phase 4 N=90 LIBERATE - LIposomal Bupivacaine vERsus Adjuncts in Total shouldErs
Post-operative Pain · Total Shoulder Arthroplasty · Osteoarthritis of the Shoulder
Primary: Total Opioid Consumption — 71.25; 90.30 MME — p=0.127
Phase 4 N=482 Evaluation of Quality of Life (QoL) in Subjects With Highly Active Relapsing Multiple Sclerosis (MS) (CLARIFY MS)
Multiple Sclerosis
Primary: Change From Baseline in Multiple Sclerosis Quality of Life-54 Questionnaire (MSQoL-54) Physical Health Composite Summary and Mental Health Composite Summary Scores at…
Phase 4 N=13 Alternate Day Versus Daily Oral Iron Therapy in Adolescents
Iron Deficiency Anemia · Heavy Menstrual Bleeding · Abnormal Uterine Bleeding
Primary: Percentage of Eligible Patients Enrolled. — 13 Participants